Anti-COKA1/ COL20A1/ bA261N11.4 functional antibody

Anti-COKA1/ COL20A1/ bA261N11.4 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to COL20A1/COL20A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0794-Ab-1/ GM-Tg-hg-SE0794-Ab-2Anti-Human COL20A1 monoclonal antibodyHuman
GM-Tg-rg-SE0794-Ab-1/ GM-Tg-rg-SE0794-Ab-2Anti-Rat COL20A1 monoclonal antibodyRat
GM-Tg-mg-SE0794-Ab-1/ GM-Tg-mg-SE0794-Ab-2Anti-Mouse COL20A1 monoclonal antibodyMouse
GM-Tg-cynog-SE0794-Ab-1/ GM-Tg-cynog-SE0794-Ab-2Anti-Cynomolgus/ Rhesus macaque COL20A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0794-Ab-1/ GM-Tg-felg-SE0794-Ab-2Anti-Feline COL20A1 monoclonal antibodyFeline
GM-Tg-cang-SE0794-Ab-1/ GM-Tg-cang-SE0794-Ab-2Anti-Canine COL20A1 monoclonal antibodyCanine
GM-Tg-bovg-SE0794-Ab-1/ GM-Tg-bovg-SE0794-Ab-2Anti-Bovine COL20A1 monoclonal antibodyBovine
GM-Tg-equg-SE0794-Ab-1/ GM-Tg-equg-SE0794-Ab-2Anti-Equine COL20A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0794-Ab-1/ GM-Tg-hg-SE0794-Ab-2; GM-Tg-rg-SE0794-Ab-1/ GM-Tg-rg-SE0794-Ab-2;
GM-Tg-mg-SE0794-Ab-1/ GM-Tg-mg-SE0794-Ab-2; GM-Tg-cynog-SE0794-Ab-1/ GM-Tg-cynog-SE0794-Ab-2;
GM-Tg-felg-SE0794-Ab-1/ GM-Tg-felg-SE0794-Ab-2; GM-Tg-cang-SE0794-Ab-1/ GM-Tg-cang-SE0794-Ab-2;
GM-Tg-bovg-SE0794-Ab-1/ GM-Tg-bovg-SE0794-Ab-2; GM-Tg-equg-SE0794-Ab-1/ GM-Tg-equg-SE0794-Ab-2
Products NameAnti-COL20A1 monoclonal antibody
Formatmab
Target NameCOL20A1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-COL20A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0794-Ag-1Recombinant multi-species COKA1/ COL20A1/ bA261N11.4 protein


    Target information

    Target IDGM-SE0794
    Target NameCOL20A1
    Gene ID57642,73368,311716,719698,485971,101101555,519501,102148845
    Gene Symbol and Synonyms1700051I12Rik,COL20A1,RGD1563901
    Uniprot AccessionQ9P218
    Uniprot Entry NameCOKA1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000101203
    Target ClassificationN/A

    The target: COL20A1, gene name: COL20A1, also named as bA261N11.4. Predicted to be located in endoplasmic reticulum lumen and extracellular region. Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.