- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-CORA1/ COL27A1/ STLS functional antibody
Anti-CORA1/ COL27A1/ STLS functional antibody for cell culture, ELISA & in-vivo assay
Go to COL27A1/COL27A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0797-Ab-1/ GM-Tg-hg-SE0797-Ab-2 | Anti-Human COL27A1 monoclonal antibody | Human |
| GM-Tg-rg-SE0797-Ab-1/ GM-Tg-rg-SE0797-Ab-2 | Anti-Rat COL27A1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0797-Ab-1/ GM-Tg-mg-SE0797-Ab-2 | Anti-Mouse COL27A1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0797-Ab-1/ GM-Tg-cynog-SE0797-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COL27A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0797-Ab-1/ GM-Tg-felg-SE0797-Ab-2 | Anti-Feline COL27A1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0797-Ab-1/ GM-Tg-cang-SE0797-Ab-2 | Anti-Canine COL27A1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0797-Ab-1/ GM-Tg-bovg-SE0797-Ab-2 | Anti-Bovine COL27A1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0797-Ab-1/ GM-Tg-equg-SE0797-Ab-2 | Anti-Equine COL27A1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0797-Ab-1/ GM-Tg-hg-SE0797-Ab-2; GM-Tg-rg-SE0797-Ab-1/ GM-Tg-rg-SE0797-Ab-2; GM-Tg-mg-SE0797-Ab-1/ GM-Tg-mg-SE0797-Ab-2; GM-Tg-cynog-SE0797-Ab-1/ GM-Tg-cynog-SE0797-Ab-2; GM-Tg-felg-SE0797-Ab-1/ GM-Tg-felg-SE0797-Ab-2; GM-Tg-cang-SE0797-Ab-1/ GM-Tg-cang-SE0797-Ab-2; GM-Tg-bovg-SE0797-Ab-1/ GM-Tg-bovg-SE0797-Ab-2; GM-Tg-equg-SE0797-Ab-1/ GM-Tg-equg-SE0797-Ab-2 |
| Products Name | Anti-COL27A1 monoclonal antibody |
| Format | mab |
| Target Name | COL27A1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-COL27A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0797-Ag-1 | Recombinant multi-species CORA1/ COL27A1/ STLS protein |
Target information
| Target ID | GM-SE0797 |
| Target Name | COL27A1 |
| Gene ID | 85301,373864,298101,708556,474811,101098263,513668,100051633 |
| Gene Symbol and Synonyms | 5730512J02Rik,COL27A1,STLS |
| Uniprot Accession | Q8IZC6,Q80ZF0 |
| Uniprot Entry Name | CORA1_HUMAN,CORA1_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000196739 |
| Target Classification | N/A |
The target: COL27A1, gene name: COL27A1, also named as STLS. This gene encodes a member of the fibrillar collagen family, and plays a role during the calcification of cartilage and the transition of cartilage to bone. The encoded protein product is a preproprotein. It includes an N-terminal signal peptide, which is followed by an N-terminal propetide, mature peptide and a C-terminal propeptide. The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains. The mature peptide is a major triple-helical region. The C-terminal propeptide, also known as COLFI domain, plays crucial roles in tissue growth and repair. Mutations in this gene cause Steel syndrome. Alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
