Anti-COSA1/ COL28A1/ COL28 functional antibody

Anti-COSA1/ COL28A1/ COL28 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to COL28A1/COL28A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0798-Ab-1/ GM-Tg-hg-SE0798-Ab-2Anti-Human COL28A1 monoclonal antibodyHuman
GM-Tg-rg-SE0798-Ab-1/ GM-Tg-rg-SE0798-Ab-2Anti-Rat COL28A1 monoclonal antibodyRat
GM-Tg-mg-SE0798-Ab-1/ GM-Tg-mg-SE0798-Ab-2Anti-Mouse COL28A1 monoclonal antibodyMouse
GM-Tg-cynog-SE0798-Ab-1/ GM-Tg-cynog-SE0798-Ab-2Anti-Cynomolgus/ Rhesus macaque COL28A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0798-Ab-1/ GM-Tg-felg-SE0798-Ab-2Anti-Feline COL28A1 monoclonal antibodyFeline
GM-Tg-cang-SE0798-Ab-1/ GM-Tg-cang-SE0798-Ab-2Anti-Canine COL28A1 monoclonal antibodyCanine
GM-Tg-bovg-SE0798-Ab-1/ GM-Tg-bovg-SE0798-Ab-2Anti-Bovine COL28A1 monoclonal antibodyBovine
GM-Tg-equg-SE0798-Ab-1/ GM-Tg-equg-SE0798-Ab-2Anti-Equine COL28A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0798-Ab-1/ GM-Tg-hg-SE0798-Ab-2; GM-Tg-rg-SE0798-Ab-1/ GM-Tg-rg-SE0798-Ab-2;
GM-Tg-mg-SE0798-Ab-1/ GM-Tg-mg-SE0798-Ab-2; GM-Tg-cynog-SE0798-Ab-1/ GM-Tg-cynog-SE0798-Ab-2;
GM-Tg-felg-SE0798-Ab-1/ GM-Tg-felg-SE0798-Ab-2; GM-Tg-cang-SE0798-Ab-1/ GM-Tg-cang-SE0798-Ab-2;
GM-Tg-bovg-SE0798-Ab-1/ GM-Tg-bovg-SE0798-Ab-2; GM-Tg-equg-SE0798-Ab-1/ GM-Tg-equg-SE0798-Ab-2
Products NameAnti-COL28A1 monoclonal antibody
Formatmab
Target NameCOL28A1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-COL28A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0798-Ag-1Recombinant multi-species COSA1/ COL28A1/ COL28 protein


    Target information

    Target IDGM-SE0798
    Target NameCOL28A1
    Gene ID340267,213945,312115,106997530,482315,101096712,100847952,100063901
    Gene Symbol and SynonymsCOL28,COL28A1,Gm466,RGD1564680
    Uniprot AccessionQ2UY09
    Uniprot Entry NameCOSA1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000215018
    Target ClassificationN/A

    The target: COL28A1, gene name: COL28A1, also named as COL28. COL28A1 belongs to a class of collagens containing von Willebrand factor (VWF; MIM 613160) type A (VWFA) domains (Veit et al., 2006 [PubMed 16330543]).[supplied by OMIM, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.