Anti-CBPA2/ CPA2 functional antibody

Anti-CBPA2/ CPA2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CPA2/CPA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0812-Ab-1/ GM-Tg-hg-SE0812-Ab-2Anti-Human CPA2 monoclonal antibodyHuman
GM-Tg-rg-SE0812-Ab-1/ GM-Tg-rg-SE0812-Ab-2Anti-Rat CPA2 monoclonal antibodyRat
GM-Tg-mg-SE0812-Ab-1/ GM-Tg-mg-SE0812-Ab-2Anti-Mouse CPA2 monoclonal antibodyMouse
GM-Tg-cynog-SE0812-Ab-1/ GM-Tg-cynog-SE0812-Ab-2Anti-Cynomolgus/ Rhesus macaque CPA2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0812-Ab-1/ GM-Tg-felg-SE0812-Ab-2Anti-Feline CPA2 monoclonal antibodyFeline
GM-Tg-cang-SE0812-Ab-1/ GM-Tg-cang-SE0812-Ab-2Anti-Canine CPA2 monoclonal antibodyCanine
GM-Tg-bovg-SE0812-Ab-1/ GM-Tg-bovg-SE0812-Ab-2Anti-Bovine CPA2 monoclonal antibodyBovine
GM-Tg-equg-SE0812-Ab-1/ GM-Tg-equg-SE0812-Ab-2Anti-Equine CPA2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0812-Ab-1/ GM-Tg-hg-SE0812-Ab-2; GM-Tg-rg-SE0812-Ab-1/ GM-Tg-rg-SE0812-Ab-2;
GM-Tg-mg-SE0812-Ab-1/ GM-Tg-mg-SE0812-Ab-2; GM-Tg-cynog-SE0812-Ab-1/ GM-Tg-cynog-SE0812-Ab-2;
GM-Tg-felg-SE0812-Ab-1/ GM-Tg-felg-SE0812-Ab-2; GM-Tg-cang-SE0812-Ab-1/ GM-Tg-cang-SE0812-Ab-2;
GM-Tg-bovg-SE0812-Ab-1/ GM-Tg-bovg-SE0812-Ab-2; GM-Tg-equg-SE0812-Ab-1/ GM-Tg-equg-SE0812-Ab-2
Products NameAnti-CPA2 monoclonal antibody
Formatmab
Target NameCPA2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CPA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0812-Ag-1Recombinant multi-species CBPA2/ CPA2 protein
    ORF Viral VectorpGMLP001203human CPA2 Lentivirus plasmid
    ORF Viral VectorvGMLP001203human CPA2 Lentivirus particle
    ORF Viral VectorpGMLPm002335mouse Cpa2 Lentivirus plasmid
    ORF Viral VectorvGMLPm002335mouse Cpa2 Lentivirus particle


    Target information

    Target IDGM-SE0812
    Target NameCPA2
    Gene ID1358,232680,296959,706684,475193,101088825,100071976
    Gene Symbol and SynonymsCPA2,CPA2(S)
    Uniprot AccessionP48052,P19222
    Uniprot Entry NameCBPA2_HUMAN,CBPA2_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158516
    Target ClassificationN/A

    The target: CPA2, gene name: CPA2, also named as . Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. [provided by RefSeq, Dec 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.