Anti-CBPA5/ CPA5 functional antibody

Anti-CBPA5/ CPA5 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CPA5/CPA5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0815-Ab-1/ GM-Tg-hg-SE0815-Ab-2Anti-Human CPA5 monoclonal antibodyHuman
GM-Tg-rg-SE0815-Ab-1/ GM-Tg-rg-SE0815-Ab-2Anti-Rat CPA5 monoclonal antibodyRat
GM-Tg-mg-SE0815-Ab-1/ GM-Tg-mg-SE0815-Ab-2Anti-Mouse CPA5 monoclonal antibodyMouse
GM-Tg-cynog-SE0815-Ab-1/ GM-Tg-cynog-SE0815-Ab-2Anti-Cynomolgus/ Rhesus macaque CPA5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0815-Ab-1/ GM-Tg-felg-SE0815-Ab-2Anti-Feline CPA5 monoclonal antibodyFeline
GM-Tg-cang-SE0815-Ab-1/ GM-Tg-cang-SE0815-Ab-2Anti-Canine CPA5 monoclonal antibodyCanine
GM-Tg-bovg-SE0815-Ab-1/ GM-Tg-bovg-SE0815-Ab-2Anti-Bovine CPA5 monoclonal antibodyBovine
GM-Tg-equg-SE0815-Ab-1/ GM-Tg-equg-SE0815-Ab-2Anti-Equine CPA5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0815-Ab-1/ GM-Tg-hg-SE0815-Ab-2; GM-Tg-rg-SE0815-Ab-1/ GM-Tg-rg-SE0815-Ab-2;
GM-Tg-mg-SE0815-Ab-1/ GM-Tg-mg-SE0815-Ab-2; GM-Tg-cynog-SE0815-Ab-1/ GM-Tg-cynog-SE0815-Ab-2;
GM-Tg-felg-SE0815-Ab-1/ GM-Tg-felg-SE0815-Ab-2; GM-Tg-cang-SE0815-Ab-1/ GM-Tg-cang-SE0815-Ab-2;
GM-Tg-bovg-SE0815-Ab-1/ GM-Tg-bovg-SE0815-Ab-2; GM-Tg-equg-SE0815-Ab-1/ GM-Tg-equg-SE0815-Ab-2
Products NameAnti-CPA5 monoclonal antibody
Formatmab
Target NameCPA5
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CPA5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0815-Ag-1Recombinant multi-species CBPA5/ CPA5 protein


    Target information

    Target IDGM-SE0815
    Target NameCPA5
    Gene ID93979,74649,408212,702974,482257,101089089,511416,100071982
    Gene Symbol and Synonyms4930430M09Rik,CPA5
    Uniprot AccessionQ8WXQ8
    Uniprot Entry NameCBPA5_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158525
    Target ClassificationN/A

    The target: CPA5, gene name: CPA5, also named as . Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.