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Anti-CBPA6/ CPA6/ CPAH functional antibody
Anti-CBPA6/ CPA6/ CPAH functional antibody for cell culture, ELISA & in-vivo assay
Go to CPA6/CPA6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0816-Ab-1/ GM-Tg-hg-SE0816-Ab-2 | Anti-Human CPA6 monoclonal antibody | Human |
| GM-Tg-rg-SE0816-Ab-1/ GM-Tg-rg-SE0816-Ab-2 | Anti-Rat CPA6 monoclonal antibody | Rat |
| GM-Tg-mg-SE0816-Ab-1/ GM-Tg-mg-SE0816-Ab-2 | Anti-Mouse CPA6 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0816-Ab-1/ GM-Tg-cynog-SE0816-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CPA6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0816-Ab-1/ GM-Tg-felg-SE0816-Ab-2 | Anti-Feline CPA6 monoclonal antibody | Feline |
| GM-Tg-cang-SE0816-Ab-1/ GM-Tg-cang-SE0816-Ab-2 | Anti-Canine CPA6 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0816-Ab-1/ GM-Tg-bovg-SE0816-Ab-2 | Anti-Bovine CPA6 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0816-Ab-1/ GM-Tg-equg-SE0816-Ab-2 | Anti-Equine CPA6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0816-Ab-1/ GM-Tg-hg-SE0816-Ab-2; GM-Tg-rg-SE0816-Ab-1/ GM-Tg-rg-SE0816-Ab-2; GM-Tg-mg-SE0816-Ab-1/ GM-Tg-mg-SE0816-Ab-2; GM-Tg-cynog-SE0816-Ab-1/ GM-Tg-cynog-SE0816-Ab-2; GM-Tg-felg-SE0816-Ab-1/ GM-Tg-felg-SE0816-Ab-2; GM-Tg-cang-SE0816-Ab-1/ GM-Tg-cang-SE0816-Ab-2; GM-Tg-bovg-SE0816-Ab-1/ GM-Tg-bovg-SE0816-Ab-2; GM-Tg-equg-SE0816-Ab-1/ GM-Tg-equg-SE0816-Ab-2 |
| Products Name | Anti-CPA6 monoclonal antibody |
| Format | mab |
| Target Name | CPA6 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CPA6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0816-Ag-1 | Recombinant multi-species CBPA6/ CPA6/ CPAH protein |
Target information
| Target ID | GM-SE0816 |
| Target Name | CPA6 |
| Gene ID | 57094,329093,312913,705117,486983,101093080,100337371,100063218 |
| Gene Symbol and Synonyms | 9030616D13Rik,CPA6,CPAH,ETL5,FEB11 |
| Uniprot Accession | Q8N4T0 |
| Uniprot Entry Name | CBPA6_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000165078 |
| Target Classification | N/A |
The target: CPA6, gene name: CPA6, also named as CPAH, ETL5, FEB11. The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome. [provided by RefSeq, May 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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