Anti-CRLD1/ CRISPLD1/ CRISP-10 functional antibody

Anti-CRLD1/ CRISPLD1/ CRISP-10 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CRISPLD1/CRISPLD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0823-Ab-1/ GM-Tg-hg-SE0823-Ab-2Anti-Human CRISPLD1 monoclonal antibodyHuman
GM-Tg-rg-SE0823-Ab-1/ GM-Tg-rg-SE0823-Ab-2Anti-Rat CRISPLD1 monoclonal antibodyRat
GM-Tg-mg-SE0823-Ab-1/ GM-Tg-mg-SE0823-Ab-2Anti-Mouse CRISPLD1 monoclonal antibodyMouse
GM-Tg-cynog-SE0823-Ab-1/ GM-Tg-cynog-SE0823-Ab-2Anti-Cynomolgus/ Rhesus macaque CRISPLD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0823-Ab-1/ GM-Tg-felg-SE0823-Ab-2Anti-Feline CRISPLD1 monoclonal antibodyFeline
GM-Tg-cang-SE0823-Ab-1/ GM-Tg-cang-SE0823-Ab-2Anti-Canine CRISPLD1 monoclonal antibodyCanine
GM-Tg-bovg-SE0823-Ab-1/ GM-Tg-bovg-SE0823-Ab-2Anti-Bovine CRISPLD1 monoclonal antibodyBovine
GM-Tg-equg-SE0823-Ab-1/ GM-Tg-equg-SE0823-Ab-2Anti-Equine CRISPLD1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0823-Ab-1/ GM-Tg-hg-SE0823-Ab-2; GM-Tg-rg-SE0823-Ab-1/ GM-Tg-rg-SE0823-Ab-2;
GM-Tg-mg-SE0823-Ab-1/ GM-Tg-mg-SE0823-Ab-2; GM-Tg-cynog-SE0823-Ab-1/ GM-Tg-cynog-SE0823-Ab-2;
GM-Tg-felg-SE0823-Ab-1/ GM-Tg-felg-SE0823-Ab-2; GM-Tg-cang-SE0823-Ab-1/ GM-Tg-cang-SE0823-Ab-2;
GM-Tg-bovg-SE0823-Ab-1/ GM-Tg-bovg-SE0823-Ab-2; GM-Tg-equg-SE0823-Ab-1/ GM-Tg-equg-SE0823-Ab-2
Products NameAnti-CRISPLD1 monoclonal antibody
Formatmab
Target NameCRISPLD1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CRISPLD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0823-Ag-1Recombinant multi-species CRLD1/ CRISPLD1/ CRISP-10 protein


    Target information

    Target IDGM-SE0823
    Target NameCRISPLD1
    Gene ID83690,83691,316482,697491,487004,101089834,536186,100050859
    Gene Symbol and SynonymsCocoacrisp,CRISP-10,CRISP10,CRISPLD1,LCRISP1,RGD1564813
    Uniprot AccessionQ9H336
    Uniprot Entry NameCRLD1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000121005
    Target ClassificationN/A

    The target: CRISPLD1, gene name: CRISPLD1, also named as CRISP-10, CRISP10, LCRISP1. Involved in face morphogenesis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.