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Anti-CRAC1/ CRTAC1/ ASPIC functional antibody
Anti-CRAC1/ CRTAC1/ ASPIC functional antibody for cell culture, ELISA & in-vivo assay
Go to CRTAC1/CRTAC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0825-Ab-1/ GM-Tg-hg-SE0825-Ab-2 | Anti-Human CRTAC1 monoclonal antibody | Human |
| GM-Tg-rg-SE0825-Ab-1/ GM-Tg-rg-SE0825-Ab-2 | Anti-Rat CRTAC1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0825-Ab-1/ GM-Tg-mg-SE0825-Ab-2 | Anti-Mouse CRTAC1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0825-Ab-1/ GM-Tg-cynog-SE0825-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CRTAC1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0825-Ab-1/ GM-Tg-felg-SE0825-Ab-2 | Anti-Feline CRTAC1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0825-Ab-1/ GM-Tg-cang-SE0825-Ab-2 | Anti-Canine CRTAC1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0825-Ab-1/ GM-Tg-bovg-SE0825-Ab-2 | Anti-Bovine CRTAC1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0825-Ab-1/ GM-Tg-equg-SE0825-Ab-2 | Anti-Equine CRTAC1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0825-Ab-1/ GM-Tg-hg-SE0825-Ab-2; GM-Tg-rg-SE0825-Ab-1/ GM-Tg-rg-SE0825-Ab-2; GM-Tg-mg-SE0825-Ab-1/ GM-Tg-mg-SE0825-Ab-2; GM-Tg-cynog-SE0825-Ab-1/ GM-Tg-cynog-SE0825-Ab-2; GM-Tg-felg-SE0825-Ab-1/ GM-Tg-felg-SE0825-Ab-2; GM-Tg-cang-SE0825-Ab-1/ GM-Tg-cang-SE0825-Ab-2; GM-Tg-bovg-SE0825-Ab-1/ GM-Tg-bovg-SE0825-Ab-2; GM-Tg-equg-SE0825-Ab-1/ GM-Tg-equg-SE0825-Ab-2 |
| Products Name | Anti-CRTAC1 monoclonal antibody |
| Format | mab |
| Target Name | CRTAC1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CRTAC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0825-Ag-1 | Recombinant multi-species CRAC1/ CRTAC1/ ASPIC protein |
| ORF Viral Vector | vGMLP004226 | human CRTAC1 Lentivirus particle |
| ORF Viral Vector | pGMLP004226 | human CRTAC1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003284 | mouse Crtac1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003284 | mouse Crtac1 Lentivirus particle |
Target information
| Target ID | GM-SE0825 |
| Target Name | CRTAC1 |
| Gene ID | 55118,72832,171438,707486,608827,101082013,100139581,100060874 |
| Gene Symbol and Synonyms | 2810454P21Rik,ASPIC,ASPIC1,CEP-68,CEP68,CRTAC1,Crtac1B,LOTUS,W307 |
| Uniprot Accession | Q9NQ79 |
| Uniprot Entry Name | CRAC1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000095713 |
| Target Classification | N/A |
The target: CRTAC1, gene name: CRTAC1, also named as ASPIC, ASPIC1, CEP-68, CEP68, LOTUS. This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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