Anti-D131B/ DEFB131B functional antibody

Anti-D131B/ DEFB131B functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to DEFB131B/DEFB131B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0877-Ab-1/ GM-Tg-hg-SE0877-Ab-2Anti-Human DEFB131B monoclonal antibodyHuman
GM-Tg-rg-SE0877-Ab-1/ GM-Tg-rg-SE0877-Ab-2Anti-Rat DEFB131B monoclonal antibodyRat
GM-Tg-mg-SE0877-Ab-1/ GM-Tg-mg-SE0877-Ab-2Anti-Mouse DEFB131B monoclonal antibodyMouse
GM-Tg-cynog-SE0877-Ab-1/ GM-Tg-cynog-SE0877-Ab-2Anti-Cynomolgus/ Rhesus macaque DEFB131B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0877-Ab-1/ GM-Tg-felg-SE0877-Ab-2Anti-Feline DEFB131B monoclonal antibodyFeline
GM-Tg-cang-SE0877-Ab-1/ GM-Tg-cang-SE0877-Ab-2Anti-Canine DEFB131B monoclonal antibodyCanine
GM-Tg-bovg-SE0877-Ab-1/ GM-Tg-bovg-SE0877-Ab-2Anti-Bovine DEFB131B monoclonal antibodyBovine
GM-Tg-equg-SE0877-Ab-1/ GM-Tg-equg-SE0877-Ab-2Anti-Equine DEFB131B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0877-Ab-1/ GM-Tg-hg-SE0877-Ab-2; GM-Tg-rg-SE0877-Ab-1/ GM-Tg-rg-SE0877-Ab-2;
GM-Tg-mg-SE0877-Ab-1/ GM-Tg-mg-SE0877-Ab-2; GM-Tg-cynog-SE0877-Ab-1/ GM-Tg-cynog-SE0877-Ab-2;
GM-Tg-felg-SE0877-Ab-1/ GM-Tg-felg-SE0877-Ab-2; GM-Tg-cang-SE0877-Ab-1/ GM-Tg-cang-SE0877-Ab-2;
GM-Tg-bovg-SE0877-Ab-1/ GM-Tg-bovg-SE0877-Ab-2; GM-Tg-equg-SE0877-Ab-1/ GM-Tg-equg-SE0877-Ab-2
Products NameAnti-DEFB131B monoclonal antibody
Formatmab
Target NameDEFB131B
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DEFB131B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0877-Ag-1Recombinant multi-species D131B/ DEFB131B protein


    Target information

    Target IDGM-SE0877
    Target NameDEFB131B
    Gene ID100129216
    Gene Symbol and SynonymsDEFB131B
    Uniprot AccessionA0A096LNP1
    Uniprot Entry NameD131B_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000225805
    Target ClassificationN/A

    The target: DEFB131B, gene name: DEFB131B, also named as . Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be active in extracellular space. .



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.