Anti-EDIL3/ DEL1 functional antibody

Anti-EDIL3/ DEL1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to EDIL3/EDIL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0898-Ab-1/ GM-Tg-hg-SE0898-Ab-2Anti-Human EDIL3 monoclonal antibodyHuman
GM-Tg-rg-SE0898-Ab-1/ GM-Tg-rg-SE0898-Ab-2Anti-Rat EDIL3 monoclonal antibodyRat
GM-Tg-mg-SE0898-Ab-1/ GM-Tg-mg-SE0898-Ab-2Anti-Mouse EDIL3 monoclonal antibodyMouse
GM-Tg-cynog-SE0898-Ab-1/ GM-Tg-cynog-SE0898-Ab-2Anti-Cynomolgus/ Rhesus macaque EDIL3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0898-Ab-1/ GM-Tg-felg-SE0898-Ab-2Anti-Feline EDIL3 monoclonal antibodyFeline
GM-Tg-cang-SE0898-Ab-1/ GM-Tg-cang-SE0898-Ab-2Anti-Canine EDIL3 monoclonal antibodyCanine
GM-Tg-bovg-SE0898-Ab-1/ GM-Tg-bovg-SE0898-Ab-2Anti-Bovine EDIL3 monoclonal antibodyBovine
GM-Tg-equg-SE0898-Ab-1/ GM-Tg-equg-SE0898-Ab-2Anti-Equine EDIL3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0898-Ab-1/ GM-Tg-hg-SE0898-Ab-2; GM-Tg-rg-SE0898-Ab-1/ GM-Tg-rg-SE0898-Ab-2;
GM-Tg-mg-SE0898-Ab-1/ GM-Tg-mg-SE0898-Ab-2; GM-Tg-cynog-SE0898-Ab-1/ GM-Tg-cynog-SE0898-Ab-2;
GM-Tg-felg-SE0898-Ab-1/ GM-Tg-felg-SE0898-Ab-2; GM-Tg-cang-SE0898-Ab-1/ GM-Tg-cang-SE0898-Ab-2;
GM-Tg-bovg-SE0898-Ab-1/ GM-Tg-bovg-SE0898-Ab-2; GM-Tg-equg-SE0898-Ab-1/ GM-Tg-equg-SE0898-Ab-2
Products NameAnti-EDIL3 monoclonal antibody
Formatmab
Target NameEDIL3
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EDIL3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0898-Ag-1Recombinant multi-species EDIL3/ DEL1 protein
    ORF Viral VectorpGMLPm002966mouse Edil3 Lentivirus plasmid
    ORF Viral VectorvGMLPm002966mouse Edil3 Lentivirus particle


    Target information

    Target IDGM-SE0898
    Target NameEDIL3
    Gene ID10085,13612,688400,693315,488919,101097205,538062,100073246
    Gene Symbol and SynonymsDel-1,DEL1,EDIL3,Sox2-cre,Sox2Cre,Tg(Sox2-cre)1Amc
    Uniprot AccessionO43854
    Uniprot Entry NameEDIL3_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164176
    Target ClassificationN/A

    The target: EDIL3, gene name: EDIL3, also named as DEL1. The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.