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Anti-FBLN4/ EFEMP2/ ARCL1B functional antibody
Anti-FBLN4/ EFEMP2/ ARCL1B functional antibody for cell culture, ELISA & in-vivo assay
Go to EFEMP2/EFEMP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0900-Ab-1/ GM-Tg-hg-SE0900-Ab-2 | Anti-Human EFEMP2 monoclonal antibody | Human |
| GM-Tg-rg-SE0900-Ab-1/ GM-Tg-rg-SE0900-Ab-2 | Anti-Rat EFEMP2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0900-Ab-1/ GM-Tg-mg-SE0900-Ab-2 | Anti-Mouse EFEMP2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0900-Ab-1/ GM-Tg-cynog-SE0900-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EFEMP2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0900-Ab-1/ GM-Tg-felg-SE0900-Ab-2 | Anti-Feline EFEMP2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0900-Ab-1/ GM-Tg-cang-SE0900-Ab-2 | Anti-Canine EFEMP2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0900-Ab-1/ GM-Tg-bovg-SE0900-Ab-2 | Anti-Bovine EFEMP2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0900-Ab-1/ GM-Tg-equg-SE0900-Ab-2 | Anti-Equine EFEMP2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0900-Ab-1/ GM-Tg-hg-SE0900-Ab-2; GM-Tg-rg-SE0900-Ab-1/ GM-Tg-rg-SE0900-Ab-2; GM-Tg-mg-SE0900-Ab-1/ GM-Tg-mg-SE0900-Ab-2; GM-Tg-cynog-SE0900-Ab-1/ GM-Tg-cynog-SE0900-Ab-2; GM-Tg-felg-SE0900-Ab-1/ GM-Tg-felg-SE0900-Ab-2; GM-Tg-cang-SE0900-Ab-1/ GM-Tg-cang-SE0900-Ab-2; GM-Tg-bovg-SE0900-Ab-1/ GM-Tg-bovg-SE0900-Ab-2; GM-Tg-equg-SE0900-Ab-1/ GM-Tg-equg-SE0900-Ab-2 |
| Products Name | Anti-EFEMP2 monoclonal antibody |
| Format | mab |
| Target Name | EFEMP2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EFEMP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0900-Ag-1 | Recombinant multi-species FBLN4/ EFEMP2/ ARCL1B protein |
Target information
| Target ID | GM-SE0900 |
| Target Name | EFEMP2 |
| Gene ID | 30008,58859,293677,721877,476020,101097593,535222,100057642 |
| Gene Symbol and Synonyms | 0610011K11Rik,ARCL1B,EFEMP2,FBLN4,Fibulin-4,MBP1,UPH1 |
| Uniprot Accession | O95967 |
| Uniprot Entry Name | FBLN4_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000172638 |
| Target Classification | N/A |
The target: EFEMP2, gene name: EFEMP2, also named as ARCL1B, FBLN4, MBP1, UPH1. A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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