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Anti-PHLD/ GPLD1/ GPIPLD functional antibody
Anti-PHLD/ GPLD1/ GPIPLD functional antibody for cell culture, ELISA & in-vivo assay
Go to GPLD1/GPLD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0954-Ab-1/ GM-Tg-hg-SE0954-Ab-2 | Anti-Human GPLD1 monoclonal antibody | Human |
| GM-Tg-rg-SE0954-Ab-1/ GM-Tg-rg-SE0954-Ab-2 | Anti-Rat GPLD1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0954-Ab-1/ GM-Tg-mg-SE0954-Ab-2 | Anti-Mouse GPLD1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0954-Ab-1/ GM-Tg-cynog-SE0954-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GPLD1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0954-Ab-1/ GM-Tg-felg-SE0954-Ab-2 | Anti-Feline GPLD1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0954-Ab-1/ GM-Tg-cang-SE0954-Ab-2 | Anti-Canine GPLD1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0954-Ab-1/ GM-Tg-bovg-SE0954-Ab-2 | Anti-Bovine GPLD1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0954-Ab-1/ GM-Tg-equg-SE0954-Ab-2 | Anti-Equine GPLD1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0954-Ab-1/ GM-Tg-hg-SE0954-Ab-2; GM-Tg-rg-SE0954-Ab-1/ GM-Tg-rg-SE0954-Ab-2; GM-Tg-mg-SE0954-Ab-1/ GM-Tg-mg-SE0954-Ab-2; GM-Tg-cynog-SE0954-Ab-1/ GM-Tg-cynog-SE0954-Ab-2; GM-Tg-felg-SE0954-Ab-1/ GM-Tg-felg-SE0954-Ab-2; GM-Tg-cang-SE0954-Ab-1/ GM-Tg-cang-SE0954-Ab-2; GM-Tg-bovg-SE0954-Ab-1/ GM-Tg-bovg-SE0954-Ab-2; GM-Tg-equg-SE0954-Ab-1/ GM-Tg-equg-SE0954-Ab-2 |
| Products Name | Anti-GPLD1 monoclonal antibody |
| Format | mab |
| Target Name | GPLD1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GPLD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0954-Ag-1 | Recombinant multi-species PHLD/ GPLD1/ GPIPLD protein |
Target information
| Target ID | GM-SE0954 |
| Target Name | GPLD1 |
| Gene ID | 2822,14756,291132,707782,478735,101088486,287025,100067517 |
| Gene Symbol and Synonyms | 6330541J12Rik,GPIPLD,GPIPLDM,GPLD1,PIGPLD,PIGPLD1,PLD |
| Uniprot Accession | P80108,Q8R2H5,P80109 |
| Uniprot Entry Name | PHLD_HUMAN,PHLD_RAT,PHLD_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112293 |
| Target Classification | N/A |
The target: GPLD1, gene name: GPLD1, also named as GPIPLD, GPIPLDM, PIGPLD, PIGPLD1, PLD. Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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