Anti-HMCN2 functional antibody

Anti-HMCN2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to HMCN2/HMCN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0967-Ab-1/ GM-Tg-hg-SE0967-Ab-2Anti-Human HMCN2 monoclonal antibodyHuman
GM-Tg-rg-SE0967-Ab-1/ GM-Tg-rg-SE0967-Ab-2Anti-Rat HMCN2 monoclonal antibodyRat
GM-Tg-mg-SE0967-Ab-1/ GM-Tg-mg-SE0967-Ab-2Anti-Mouse HMCN2 monoclonal antibodyMouse
GM-Tg-cynog-SE0967-Ab-1/ GM-Tg-cynog-SE0967-Ab-2Anti-Cynomolgus/ Rhesus macaque HMCN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0967-Ab-1/ GM-Tg-felg-SE0967-Ab-2Anti-Feline HMCN2 monoclonal antibodyFeline
GM-Tg-cang-SE0967-Ab-1/ GM-Tg-cang-SE0967-Ab-2Anti-Canine HMCN2 monoclonal antibodyCanine
GM-Tg-bovg-SE0967-Ab-1/ GM-Tg-bovg-SE0967-Ab-2Anti-Bovine HMCN2 monoclonal antibodyBovine
GM-Tg-equg-SE0967-Ab-1/ GM-Tg-equg-SE0967-Ab-2Anti-Equine HMCN2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0967-Ab-1/ GM-Tg-hg-SE0967-Ab-2; GM-Tg-rg-SE0967-Ab-1/ GM-Tg-rg-SE0967-Ab-2;
GM-Tg-mg-SE0967-Ab-1/ GM-Tg-mg-SE0967-Ab-2; GM-Tg-cynog-SE0967-Ab-1/ GM-Tg-cynog-SE0967-Ab-2;
GM-Tg-felg-SE0967-Ab-1/ GM-Tg-felg-SE0967-Ab-2; GM-Tg-cang-SE0967-Ab-1/ GM-Tg-cang-SE0967-Ab-2;
GM-Tg-bovg-SE0967-Ab-1/ GM-Tg-bovg-SE0967-Ab-2; GM-Tg-equg-SE0967-Ab-1/ GM-Tg-equg-SE0967-Ab-2
Products NameAnti-HMCN2 monoclonal antibody
Formatmab
Target NameHMCN2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-HMCN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0967-Ag-1Recombinant multi-species HMCN2 protein


    Target information

    Target IDGM-SE0967
    Target NameHMCN2
    Gene ID256158,665700,686132,720622,491293,101097281,534512,100069798
    Gene Symbol and SynonymsD030068H01,HMCN2
    Uniprot AccessionQ8NDA2
    Uniprot Entry NameHMCN2_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000148357
    Target ClassificationN/A

    The target: HMCN2, gene name: HMCN2, also named as . Predicted to enable calcium ion binding activity. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in cell adhesion. Located in collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.