Anti-HMSD/ HMSDV/ HMSD functional antibody

Anti-HMSD/ HMSDV/ HMSD functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to HMSD/HMSD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0968-Ab-1/ GM-Tg-hg-SE0968-Ab-2Anti-Human HMSD monoclonal antibodyHuman
GM-Tg-rg-SE0968-Ab-1/ GM-Tg-rg-SE0968-Ab-2Anti-Rat HMSD monoclonal antibodyRat
GM-Tg-mg-SE0968-Ab-1/ GM-Tg-mg-SE0968-Ab-2Anti-Mouse HMSD monoclonal antibodyMouse
GM-Tg-cynog-SE0968-Ab-1/ GM-Tg-cynog-SE0968-Ab-2Anti-Cynomolgus/ Rhesus macaque HMSD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0968-Ab-1/ GM-Tg-felg-SE0968-Ab-2Anti-Feline HMSD monoclonal antibodyFeline
GM-Tg-cang-SE0968-Ab-1/ GM-Tg-cang-SE0968-Ab-2Anti-Canine HMSD monoclonal antibodyCanine
GM-Tg-bovg-SE0968-Ab-1/ GM-Tg-bovg-SE0968-Ab-2Anti-Bovine HMSD monoclonal antibodyBovine
GM-Tg-equg-SE0968-Ab-1/ GM-Tg-equg-SE0968-Ab-2Anti-Equine HMSD monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0968-Ab-1/ GM-Tg-hg-SE0968-Ab-2; GM-Tg-rg-SE0968-Ab-1/ GM-Tg-rg-SE0968-Ab-2;
GM-Tg-mg-SE0968-Ab-1/ GM-Tg-mg-SE0968-Ab-2; GM-Tg-cynog-SE0968-Ab-1/ GM-Tg-cynog-SE0968-Ab-2;
GM-Tg-felg-SE0968-Ab-1/ GM-Tg-felg-SE0968-Ab-2; GM-Tg-cang-SE0968-Ab-1/ GM-Tg-cang-SE0968-Ab-2;
GM-Tg-bovg-SE0968-Ab-1/ GM-Tg-bovg-SE0968-Ab-2; GM-Tg-equg-SE0968-Ab-1/ GM-Tg-equg-SE0968-Ab-2
Products NameAnti-HMSD monoclonal antibody
Formatmab
Target NameHMSD
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-HMSD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0968-Ag-1Recombinant multi-species HMSD/ HMSDV/ HMSD protein


    Target information

    Target IDGM-SE0968
    Target NameHMSD
    Gene ID284293
    Gene Symbol and SynonymsACC-6,ACC6,C18orf53,HMSD,HSMD-v
    Uniprot AccessionA8MTL9, P0C7T4
    Uniprot Entry NameHMSDV_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000221887
    Target ClassificationN/A

    The target: HMSD, gene name: HMSD, also named as ACC-6, ACC6, C18orf53, HSMD-v. This gene encodes a serpin-domain containing protein that may function as a serine protease inhibitor. This gene is primarily expressed in cells of myeloid lineage. A polymorphism in this gene may result in the expression a splice variant that encodes a minor histocompatibility antigen. [provided by RefSeq, Oct 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.