Anti-IGIP/ C5orf53 functional antibody

Anti-IGIP/ C5orf53 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to IGIP/IGIP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1020-Ab-1/ GM-Tg-hg-SE1020-Ab-2Anti-Human IGIP monoclonal antibodyHuman
GM-Tg-rg-SE1020-Ab-1/ GM-Tg-rg-SE1020-Ab-2Anti-Rat IGIP monoclonal antibodyRat
GM-Tg-mg-SE1020-Ab-1/ GM-Tg-mg-SE1020-Ab-2Anti-Mouse IGIP monoclonal antibodyMouse
GM-Tg-cynog-SE1020-Ab-1/ GM-Tg-cynog-SE1020-Ab-2Anti-Cynomolgus/ Rhesus macaque IGIP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1020-Ab-1/ GM-Tg-felg-SE1020-Ab-2Anti-Feline IGIP monoclonal antibodyFeline
GM-Tg-cang-SE1020-Ab-1/ GM-Tg-cang-SE1020-Ab-2Anti-Canine IGIP monoclonal antibodyCanine
GM-Tg-bovg-SE1020-Ab-1/ GM-Tg-bovg-SE1020-Ab-2Anti-Bovine IGIP monoclonal antibodyBovine
GM-Tg-equg-SE1020-Ab-1/ GM-Tg-equg-SE1020-Ab-2Anti-Equine IGIP monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1020-Ab-1/ GM-Tg-hg-SE1020-Ab-2; GM-Tg-rg-SE1020-Ab-1/ GM-Tg-rg-SE1020-Ab-2;
GM-Tg-mg-SE1020-Ab-1/ GM-Tg-mg-SE1020-Ab-2; GM-Tg-cynog-SE1020-Ab-1/ GM-Tg-cynog-SE1020-Ab-2;
GM-Tg-felg-SE1020-Ab-1/ GM-Tg-felg-SE1020-Ab-2; GM-Tg-cang-SE1020-Ab-1/ GM-Tg-cang-SE1020-Ab-2;
GM-Tg-bovg-SE1020-Ab-1/ GM-Tg-bovg-SE1020-Ab-2; GM-Tg-equg-SE1020-Ab-1/ GM-Tg-equg-SE1020-Ab-2
Products NameAnti-IGIP monoclonal antibody
Formatmab
Target NameIGIP
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IGIP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1020-Ag-1Recombinant multi-species IGIP/ C5orf53 protein
    ORF Viral VectorvGMLP004659human IGIP Lentivirus particle
    ORF Viral VectorpGMLP004659human IGIP Lentivirus plasmid
    ORF Viral VectorpGMLPm001226mouse Igip Lentivirus plasmid
    ORF Viral VectorvGMLPm001226mouse Igip Lentivirus particle


    Target information

    Target IDGM-SE1020
    Target NameIGIP
    Gene ID492311,109169,100363266,100423854,101092824,404059,100629973
    Gene Symbol and Synonyms6330403M23Rik,C5orf53,C6H5orf53,IGIP
    Uniprot AccessionA6NJ69,P0C7I2
    Uniprot Entry NameIGIP_HUMAN,IGIP_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000182700
    Target ClassificationN/A

    The target: IGIP, gene name: IGIP, also named as C5orf53. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.