Anti-IGLL5/ IGL/ IGLV functional antibody

Anti-IGLL5/ IGL/ IGLV functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to IGLL5/IGLL5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1021-Ab-1/ GM-Tg-hg-SE1021-Ab-2Anti-Human IGLL5 monoclonal antibodyHuman
GM-Tg-rg-SE1021-Ab-1/ GM-Tg-rg-SE1021-Ab-2Anti-Rat IGLL5 monoclonal antibodyRat
GM-Tg-mg-SE1021-Ab-1/ GM-Tg-mg-SE1021-Ab-2Anti-Mouse IGLL5 monoclonal antibodyMouse
GM-Tg-cynog-SE1021-Ab-1/ GM-Tg-cynog-SE1021-Ab-2Anti-Cynomolgus/ Rhesus macaque IGLL5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1021-Ab-1/ GM-Tg-felg-SE1021-Ab-2Anti-Feline IGLL5 monoclonal antibodyFeline
GM-Tg-cang-SE1021-Ab-1/ GM-Tg-cang-SE1021-Ab-2Anti-Canine IGLL5 monoclonal antibodyCanine
GM-Tg-bovg-SE1021-Ab-1/ GM-Tg-bovg-SE1021-Ab-2Anti-Bovine IGLL5 monoclonal antibodyBovine
GM-Tg-equg-SE1021-Ab-1/ GM-Tg-equg-SE1021-Ab-2Anti-Equine IGLL5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1021-Ab-1/ GM-Tg-hg-SE1021-Ab-2; GM-Tg-rg-SE1021-Ab-1/ GM-Tg-rg-SE1021-Ab-2;
GM-Tg-mg-SE1021-Ab-1/ GM-Tg-mg-SE1021-Ab-2; GM-Tg-cynog-SE1021-Ab-1/ GM-Tg-cynog-SE1021-Ab-2;
GM-Tg-felg-SE1021-Ab-1/ GM-Tg-felg-SE1021-Ab-2; GM-Tg-cang-SE1021-Ab-1/ GM-Tg-cang-SE1021-Ab-2;
GM-Tg-bovg-SE1021-Ab-1/ GM-Tg-bovg-SE1021-Ab-2; GM-Tg-equg-SE1021-Ab-1/ GM-Tg-equg-SE1021-Ab-2
Products NameAnti-IGLL5 monoclonal antibody
Formatmab
Target NameIGLL5
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IGLL5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1021-Ag-1Recombinant multi-species IGLL5/ IGL/ IGLV protein


    Target information

    Target IDGM-SE1021
    Target NameIGLL5
    Gene ID100423062,16136,100360919
    Gene Symbol and SynonymsIGL,Igl-5,Igll,Igll1,IGLL5,IGLV,Lambda5,VL-MAR
    Uniprot AccessionB9A064
    Uniprot Entry NameIGLL5_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000254709
    Target ClassificationN/A

    The target: IGLL5, gene name: IGLL5, also named as IGL, IGLV, VL-MAR. This gene encodes one of the immunoglobulin lambda-like polypeptides. It is located within the immunoglobulin lambda locus but it does not require somatic rearrangement for expression. The first exon of this gene is unrelated to immunoglobulin variable genes; the second and third exons are the immunoglobulin lambda joining 1 and the immunoglobulin lambda constant 1 gene segments. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.