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Anti-IL3/ IL-3/ MCGF functional antibody
Anti-IL3/ IL-3/ MCGF functional antibody for cell culture, ELISA & in-vivo assay
Go to IL3/IL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1027-Ab-1/ GM-Tg-hg-SE1027-Ab-2 | Anti-Human IL3 monoclonal antibody | Human |
| GM-Tg-rg-SE1027-Ab-1/ GM-Tg-rg-SE1027-Ab-2 | Anti-Rat IL3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1027-Ab-1/ GM-Tg-mg-SE1027-Ab-2 | Anti-Mouse IL3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1027-Ab-1/ GM-Tg-cynog-SE1027-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IL3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1027-Ab-1/ GM-Tg-felg-SE1027-Ab-2 | Anti-Feline IL3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1027-Ab-1/ GM-Tg-cang-SE1027-Ab-2 | Anti-Canine IL3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1027-Ab-1/ GM-Tg-bovg-SE1027-Ab-2 | Anti-Bovine IL3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1027-Ab-1/ GM-Tg-equg-SE1027-Ab-2 | Anti-Equine IL3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1027-Ab-1/ GM-Tg-hg-SE1027-Ab-2; GM-Tg-rg-SE1027-Ab-1/ GM-Tg-rg-SE1027-Ab-2; GM-Tg-mg-SE1027-Ab-1/ GM-Tg-mg-SE1027-Ab-2; GM-Tg-cynog-SE1027-Ab-1/ GM-Tg-cynog-SE1027-Ab-2; GM-Tg-felg-SE1027-Ab-1/ GM-Tg-felg-SE1027-Ab-2; GM-Tg-cang-SE1027-Ab-1/ GM-Tg-cang-SE1027-Ab-2; GM-Tg-bovg-SE1027-Ab-1/ GM-Tg-bovg-SE1027-Ab-2; GM-Tg-equg-SE1027-Ab-1/ GM-Tg-equg-SE1027-Ab-2 |
| Products Name | Anti-IL3 monoclonal antibody |
| Format | mab |
| Target Name | IL3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1027-Ag-1 | Recombinant multi-species IL3/ IL-3/ MCGF protein |
| ORF Viral Vector | pGMLP000459 | human IL3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000459 | human IL3 Lentivirus particle |
| ORF Viral Vector | vGMAP000287 | Human IL3 Adenovirus particle |
| ORF Viral Vector | pGMAP000287 | Human IL3 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000118 | mouse Il3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000118 | mouse Il3 Lentivirus particle |
Target information
| Target ID | GM-SE1027 |
| Target Name | IL3 |
| Gene ID | 3562,16187,24495,706946,280823 |
| Gene Symbol and Synonyms | BPA,Csfmu,HCGF,IL-3,IL3,MCGF,MULTI-CSF,PSF |
| Uniprot Accession | P08700,P04823,P25140,Q9BDX4,P49875 |
| Uniprot Entry Name | IL3_HUMAN,IL3_MACMU,IL3_RAT,IL3_CANLF,IL3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000164399 |
| Target Classification | N/A |
The target: IL3, gene name: IL3, also named as IL-3, MCGF, MULTI-CSF. The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
