Anti-MATN2 functional antibody

Anti-MATN2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to MATN2/MATN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1091-Ab-1/ GM-Tg-hg-SE1091-Ab-2Anti-Human MATN2 monoclonal antibodyHuman
GM-Tg-rg-SE1091-Ab-1/ GM-Tg-rg-SE1091-Ab-2Anti-Rat MATN2 monoclonal antibodyRat
GM-Tg-mg-SE1091-Ab-1/ GM-Tg-mg-SE1091-Ab-2Anti-Mouse MATN2 monoclonal antibodyMouse
GM-Tg-cynog-SE1091-Ab-1/ GM-Tg-cynog-SE1091-Ab-2Anti-Cynomolgus/ Rhesus macaque MATN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1091-Ab-1/ GM-Tg-felg-SE1091-Ab-2Anti-Feline MATN2 monoclonal antibodyFeline
GM-Tg-cang-SE1091-Ab-1/ GM-Tg-cang-SE1091-Ab-2Anti-Canine MATN2 monoclonal antibodyCanine
GM-Tg-bovg-SE1091-Ab-1/ GM-Tg-bovg-SE1091-Ab-2Anti-Bovine MATN2 monoclonal antibodyBovine
GM-Tg-equg-SE1091-Ab-1/ GM-Tg-equg-SE1091-Ab-2Anti-Equine MATN2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1091-Ab-1/ GM-Tg-hg-SE1091-Ab-2; GM-Tg-rg-SE1091-Ab-1/ GM-Tg-rg-SE1091-Ab-2;
GM-Tg-mg-SE1091-Ab-1/ GM-Tg-mg-SE1091-Ab-2; GM-Tg-cynog-SE1091-Ab-1/ GM-Tg-cynog-SE1091-Ab-2;
GM-Tg-felg-SE1091-Ab-1/ GM-Tg-felg-SE1091-Ab-2; GM-Tg-cang-SE1091-Ab-1/ GM-Tg-cang-SE1091-Ab-2;
GM-Tg-bovg-SE1091-Ab-1/ GM-Tg-bovg-SE1091-Ab-2; GM-Tg-equg-SE1091-Ab-1/ GM-Tg-equg-SE1091-Ab-2
Products NameAnti-MATN2 monoclonal antibody
Formatmab
Target NameMATN2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MATN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1091-Ag-1Recombinant multi-species MATN2 protein
    ORF Viral VectorpGMLPm004430mouse Matn2 Lentivirus plasmid
    ORF Viral VectorvGMLPm004430mouse Matn2 Lentivirus particle


    Target information

    Target IDGM-SE1091
    Target NameMATN2
    Gene ID4147,17181,299996,705161,491431,101092913,781953,100055555
    Gene Symbol and SynonymsCrtm2,MATN2,matrilin-2
    Uniprot AccessionO00339
    Uniprot Entry NameMATN2_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132561
    Target ClassificationN/A

    The target: MATN2, gene name: MATN2, also named as . This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.