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Anti-MATN3/ DIPOA/ EDM5 functional antibody
Anti-MATN3/ DIPOA/ EDM5 functional antibody for cell culture, ELISA & in-vivo assay
Go to MATN3/MATN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1092-Ab-1/ GM-Tg-hg-SE1092-Ab-2 | Anti-Human MATN3 monoclonal antibody | Human |
| GM-Tg-rg-SE1092-Ab-1/ GM-Tg-rg-SE1092-Ab-2 | Anti-Rat MATN3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1092-Ab-1/ GM-Tg-mg-SE1092-Ab-2 | Anti-Mouse MATN3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1092-Ab-1/ GM-Tg-cynog-SE1092-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MATN3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1092-Ab-1/ GM-Tg-felg-SE1092-Ab-2 | Anti-Feline MATN3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1092-Ab-1/ GM-Tg-cang-SE1092-Ab-2 | Anti-Canine MATN3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1092-Ab-1/ GM-Tg-bovg-SE1092-Ab-2 | Anti-Bovine MATN3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1092-Ab-1/ GM-Tg-equg-SE1092-Ab-2 | Anti-Equine MATN3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1092-Ab-1/ GM-Tg-hg-SE1092-Ab-2; GM-Tg-rg-SE1092-Ab-1/ GM-Tg-rg-SE1092-Ab-2; GM-Tg-mg-SE1092-Ab-1/ GM-Tg-mg-SE1092-Ab-2; GM-Tg-cynog-SE1092-Ab-1/ GM-Tg-cynog-SE1092-Ab-2; GM-Tg-felg-SE1092-Ab-1/ GM-Tg-felg-SE1092-Ab-2; GM-Tg-cang-SE1092-Ab-1/ GM-Tg-cang-SE1092-Ab-2; GM-Tg-bovg-SE1092-Ab-1/ GM-Tg-bovg-SE1092-Ab-2; GM-Tg-equg-SE1092-Ab-1/ GM-Tg-equg-SE1092-Ab-2 |
| Products Name | Anti-MATN3 monoclonal antibody |
| Format | mab |
| Target Name | MATN3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MATN3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1092-Ag-1 | Recombinant multi-species MATN3/ DIPOA/ EDM5 protein |
| ORF Viral Vector | pGMLPm004860 | mouse Matn3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004860 | mouse Matn3 Lentivirus particle |
Target information
| Target ID | GM-SE1092 |
| Target Name | MATN3 |
| Gene ID | 4148,17182,313954,716677,482985,101080276,540041,100071902 |
| Gene Symbol and Synonyms | DIPOA,EDM5,HOA,MATN3,OADIP,OS2,SEMDBCD |
| Uniprot Accession | O15232 |
| Uniprot Entry Name | MATN3_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000132031 |
| Target Classification | N/A |
The target: MATN3, gene name: MATN3, also named as DIPOA, EDM5, HOA, OADIP, OS2. This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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