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Anti-MMP19/ CODA/ MMP18 functional antibody
Anti-MMP19/ CODA/ MMP18 functional antibody for cell culture, ELISA & in-vivo assay
Go to MMP19/MMP19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1100-Ab-1/ GM-Tg-hg-SE1100-Ab-2 | Anti-Human MMP19 monoclonal antibody | Human |
| GM-Tg-rg-SE1100-Ab-1/ GM-Tg-rg-SE1100-Ab-2 | Anti-Rat MMP19 monoclonal antibody | Rat |
| GM-Tg-mg-SE1100-Ab-1/ GM-Tg-mg-SE1100-Ab-2 | Anti-Mouse MMP19 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1100-Ab-1/ GM-Tg-cynog-SE1100-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MMP19 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1100-Ab-1/ GM-Tg-felg-SE1100-Ab-2 | Anti-Feline MMP19 monoclonal antibody | Feline |
| GM-Tg-cang-SE1100-Ab-1/ GM-Tg-cang-SE1100-Ab-2 | Anti-Canine MMP19 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1100-Ab-1/ GM-Tg-bovg-SE1100-Ab-2 | Anti-Bovine MMP19 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1100-Ab-1/ GM-Tg-equg-SE1100-Ab-2 | Anti-Equine MMP19 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1100-Ab-1/ GM-Tg-hg-SE1100-Ab-2; GM-Tg-rg-SE1100-Ab-1/ GM-Tg-rg-SE1100-Ab-2; GM-Tg-mg-SE1100-Ab-1/ GM-Tg-mg-SE1100-Ab-2; GM-Tg-cynog-SE1100-Ab-1/ GM-Tg-cynog-SE1100-Ab-2; GM-Tg-felg-SE1100-Ab-1/ GM-Tg-felg-SE1100-Ab-2; GM-Tg-cang-SE1100-Ab-1/ GM-Tg-cang-SE1100-Ab-2; GM-Tg-bovg-SE1100-Ab-1/ GM-Tg-bovg-SE1100-Ab-2; GM-Tg-equg-SE1100-Ab-1/ GM-Tg-equg-SE1100-Ab-2 |
| Products Name | Anti-MMP19 monoclonal antibody |
| Format | mab |
| Target Name | MMP19 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MMP19 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1100-Ag-1 | Recombinant multi-species MMP19/ CODA/ MMP18 protein |
| ORF Viral Vector | pGMAAV000246 | human MMP19 AAV plasmid |
| ORF Viral Vector | vGMAAV000246 | human MMP19 AAV particle |
Target information
| Target ID | GM-SE1100 |
| Target Name | MMP19 |
| Gene ID | 4327,58223,304608,710111,606853,101092032,533203,100058984 |
| Gene Symbol and Synonyms | CODA,MMP18,MMP19,RASI-1 |
| Uniprot Accession | Q99542 |
| Uniprot Entry Name | MMP19_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000123342 |
| Target Classification | N/A |
The target: MMP19, gene name: MMP19, also named as CODA, MMP18, RASI-1. This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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