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Anti-MMP28/ EPILYSIN/ MM28 functional antibody
Anti-MMP28/ EPILYSIN/ MM28 functional antibody for cell culture, ELISA & in-vivo assay
Go to MMP28/MMP28 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1102-Ab-1/ GM-Tg-hg-SE1102-Ab-2 | Anti-Human MMP28 monoclonal antibody | Human |
| GM-Tg-rg-SE1102-Ab-1/ GM-Tg-rg-SE1102-Ab-2 | Anti-Rat MMP28 monoclonal antibody | Rat |
| GM-Tg-mg-SE1102-Ab-1/ GM-Tg-mg-SE1102-Ab-2 | Anti-Mouse MMP28 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1102-Ab-1/ GM-Tg-cynog-SE1102-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MMP28 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1102-Ab-1/ GM-Tg-felg-SE1102-Ab-2 | Anti-Feline MMP28 monoclonal antibody | Feline |
| GM-Tg-cang-SE1102-Ab-1/ GM-Tg-cang-SE1102-Ab-2 | Anti-Canine MMP28 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1102-Ab-1/ GM-Tg-bovg-SE1102-Ab-2 | Anti-Bovine MMP28 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1102-Ab-1/ GM-Tg-equg-SE1102-Ab-2 | Anti-Equine MMP28 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1102-Ab-1/ GM-Tg-hg-SE1102-Ab-2; GM-Tg-rg-SE1102-Ab-1/ GM-Tg-rg-SE1102-Ab-2; GM-Tg-mg-SE1102-Ab-1/ GM-Tg-mg-SE1102-Ab-2; GM-Tg-cynog-SE1102-Ab-1/ GM-Tg-cynog-SE1102-Ab-2; GM-Tg-felg-SE1102-Ab-1/ GM-Tg-felg-SE1102-Ab-2; GM-Tg-cang-SE1102-Ab-1/ GM-Tg-cang-SE1102-Ab-2; GM-Tg-bovg-SE1102-Ab-1/ GM-Tg-bovg-SE1102-Ab-2; GM-Tg-equg-SE1102-Ab-1/ GM-Tg-equg-SE1102-Ab-2 |
| Products Name | Anti-MMP28 monoclonal antibody |
| Format | mab |
| Target Name | MMP28 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MMP28 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1102-Ag-1 | Recombinant multi-species MMP28/ EPILYSIN/ MM28 protein |
Target information
| Target ID | GM-SE1102 |
| Target Name | MMP28 |
| Gene ID | 79148,118453,303384,574250,491136,101085251,519276,100071568 |
| Gene Symbol and Synonyms | D130023P12,EPILYSIN,MM28,MMP-25,MMP-28,MMP25,MMP28 |
| Uniprot Accession | Q9H239 |
| Uniprot Entry Name | MMP28_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000271447 |
| Target Classification | N/A |
The target: MMP28, gene name: MMP28, also named as EPILYSIN, MM28, MMP-25, MMP-28, MMP25. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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