Anti-NT5D3/ NT5DC3/ TU12B1-TY functional antibody

Anti-NT5D3/ NT5DC3/ TU12B1-TY functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to NT5DC3/NT5DC3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1138-Ab-1/ GM-Tg-hg-SE1138-Ab-2Anti-Human NT5DC3 monoclonal antibodyHuman
GM-Tg-rg-SE1138-Ab-1/ GM-Tg-rg-SE1138-Ab-2Anti-Rat NT5DC3 monoclonal antibodyRat
GM-Tg-mg-SE1138-Ab-1/ GM-Tg-mg-SE1138-Ab-2Anti-Mouse NT5DC3 monoclonal antibodyMouse
GM-Tg-cynog-SE1138-Ab-1/ GM-Tg-cynog-SE1138-Ab-2Anti-Cynomolgus/ Rhesus macaque NT5DC3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1138-Ab-1/ GM-Tg-felg-SE1138-Ab-2Anti-Feline NT5DC3 monoclonal antibodyFeline
GM-Tg-cang-SE1138-Ab-1/ GM-Tg-cang-SE1138-Ab-2Anti-Canine NT5DC3 monoclonal antibodyCanine
GM-Tg-bovg-SE1138-Ab-1/ GM-Tg-bovg-SE1138-Ab-2Anti-Bovine NT5DC3 monoclonal antibodyBovine
GM-Tg-equg-SE1138-Ab-1/ GM-Tg-equg-SE1138-Ab-2Anti-Equine NT5DC3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1138-Ab-1/ GM-Tg-hg-SE1138-Ab-2; GM-Tg-rg-SE1138-Ab-1/ GM-Tg-rg-SE1138-Ab-2;
GM-Tg-mg-SE1138-Ab-1/ GM-Tg-mg-SE1138-Ab-2; GM-Tg-cynog-SE1138-Ab-1/ GM-Tg-cynog-SE1138-Ab-2;
GM-Tg-felg-SE1138-Ab-1/ GM-Tg-felg-SE1138-Ab-2; GM-Tg-cang-SE1138-Ab-1/ GM-Tg-cang-SE1138-Ab-2;
GM-Tg-bovg-SE1138-Ab-1/ GM-Tg-bovg-SE1138-Ab-2; GM-Tg-equg-SE1138-Ab-1/ GM-Tg-equg-SE1138-Ab-2
Products NameAnti-NT5DC3 monoclonal antibody
Formatmab
Target NameNT5DC3
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NT5DC3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1138-Ag-1Recombinant multi-species NT5D3/ NT5DC3/ TU12B1-TY protein


    Target information

    Target IDGM-SE1138
    Target NameNT5DC3
    Gene ID51559,103466,691922,699285,612224,101083526,520927,100067545
    Gene Symbol and SynonymsC630002B14Rik,NT5DC3,TU12B1-TY,TU12B1TY
    Uniprot AccessionQ86UY8
    Uniprot Entry NameNT5D3_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000111696
    Target ClassificationN/A

    The target: NT5DC3, gene name: NT5DC3, also named as TU12B1-TY, TU12B1TY. Predicted to enable 5'-nucleotidase activity. Predicted to be involved in dephosphorylation. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.