Anti-ODAPH/ AI2A4/ C4orf26 functional antibody

Anti-ODAPH/ AI2A4/ C4orf26 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ODAPH/ODAPH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1147-Ab-1/ GM-Tg-hg-SE1147-Ab-2Anti-Human ODAPH monoclonal antibodyHuman
GM-Tg-rg-SE1147-Ab-1/ GM-Tg-rg-SE1147-Ab-2Anti-Rat ODAPH monoclonal antibodyRat
GM-Tg-mg-SE1147-Ab-1/ GM-Tg-mg-SE1147-Ab-2Anti-Mouse ODAPH monoclonal antibodyMouse
GM-Tg-cynog-SE1147-Ab-1/ GM-Tg-cynog-SE1147-Ab-2Anti-Cynomolgus/ Rhesus macaque ODAPH monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1147-Ab-1/ GM-Tg-felg-SE1147-Ab-2Anti-Feline ODAPH monoclonal antibodyFeline
GM-Tg-cang-SE1147-Ab-1/ GM-Tg-cang-SE1147-Ab-2Anti-Canine ODAPH monoclonal antibodyCanine
GM-Tg-bovg-SE1147-Ab-1/ GM-Tg-bovg-SE1147-Ab-2Anti-Bovine ODAPH monoclonal antibodyBovine
GM-Tg-equg-SE1147-Ab-1/ GM-Tg-equg-SE1147-Ab-2Anti-Equine ODAPH monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1147-Ab-1/ GM-Tg-hg-SE1147-Ab-2; GM-Tg-rg-SE1147-Ab-1/ GM-Tg-rg-SE1147-Ab-2;
GM-Tg-mg-SE1147-Ab-1/ GM-Tg-mg-SE1147-Ab-2; GM-Tg-cynog-SE1147-Ab-1/ GM-Tg-cynog-SE1147-Ab-2;
GM-Tg-felg-SE1147-Ab-1/ GM-Tg-felg-SE1147-Ab-2; GM-Tg-cang-SE1147-Ab-1/ GM-Tg-cang-SE1147-Ab-2;
GM-Tg-bovg-SE1147-Ab-1/ GM-Tg-bovg-SE1147-Ab-2; GM-Tg-equg-SE1147-Ab-1/ GM-Tg-equg-SE1147-Ab-2
Products NameAnti-ODAPH monoclonal antibody
Formatmab
Target NameODAPH
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ODAPH benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1147-Ag-1Recombinant multi-species ODAPH/ AI2A4/ C4orf26 protein


    Target information

    Target IDGM-SE1147
    Target NameODAPH
    Gene ID152816,381651,100911949,100423169,100685496,101092359,100295382,100057498
    Gene Symbol and SynonymsAI2A4,C32H4orf26,C3H4orf26,C4orf26,C5H4orf26,C6H4orf26,CB1H4orf26,Gm1045,Gm1045-a,Gm1045-b,ODAPH
    Uniprot AccessionQ17RF5,A0A0G2K6Z9
    Uniprot Entry NameODAPH_HUMAN,ODAPH_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000174792
    Target ClassificationN/A

    The target: ODAPH, gene name: ODAPH, also named as AI2A4, C4orf26. Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene is thought to encode an extracellular matrix acidic phosphoprotein that has a function in enamel mineralization during amelogenesis. Mutations in this gene are associated with recessive hypomineralized amelogenesis imperfecta. [provided by RefSeq, Oct 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.