Anti-NOE3/ OLFM3/ NOELIN3 functional antibody

Anti-NOE3/ OLFM3/ NOELIN3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to OLFM3/OLFM3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1150-Ab-1/ GM-Tg-hg-SE1150-Ab-2Anti-Human OLFM3 monoclonal antibodyHuman
GM-Tg-rg-SE1150-Ab-1/ GM-Tg-rg-SE1150-Ab-2Anti-Rat OLFM3 monoclonal antibodyRat
GM-Tg-mg-SE1150-Ab-1/ GM-Tg-mg-SE1150-Ab-2Anti-Mouse OLFM3 monoclonal antibodyMouse
GM-Tg-cynog-SE1150-Ab-1/ GM-Tg-cynog-SE1150-Ab-2Anti-Cynomolgus/ Rhesus macaque OLFM3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1150-Ab-1/ GM-Tg-felg-SE1150-Ab-2Anti-Feline OLFM3 monoclonal antibodyFeline
GM-Tg-cang-SE1150-Ab-1/ GM-Tg-cang-SE1150-Ab-2Anti-Canine OLFM3 monoclonal antibodyCanine
GM-Tg-bovg-SE1150-Ab-1/ GM-Tg-bovg-SE1150-Ab-2Anti-Bovine OLFM3 monoclonal antibodyBovine
GM-Tg-equg-SE1150-Ab-1/ GM-Tg-equg-SE1150-Ab-2Anti-Equine OLFM3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1150-Ab-1/ GM-Tg-hg-SE1150-Ab-2; GM-Tg-rg-SE1150-Ab-1/ GM-Tg-rg-SE1150-Ab-2;
GM-Tg-mg-SE1150-Ab-1/ GM-Tg-mg-SE1150-Ab-2; GM-Tg-cynog-SE1150-Ab-1/ GM-Tg-cynog-SE1150-Ab-2;
GM-Tg-felg-SE1150-Ab-1/ GM-Tg-felg-SE1150-Ab-2; GM-Tg-cang-SE1150-Ab-1/ GM-Tg-cang-SE1150-Ab-2;
GM-Tg-bovg-SE1150-Ab-1/ GM-Tg-bovg-SE1150-Ab-2; GM-Tg-equg-SE1150-Ab-1/ GM-Tg-equg-SE1150-Ab-2
Products NameAnti-OLFM3 monoclonal antibody
Formatmab
Target NameOLFM3
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OLFM3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1150-Ag-1Recombinant multi-species NOE3/ OLFM3/ NOELIN3 protein


    Target information

    Target IDGM-SE1150
    Target NameOLFM3
    Gene ID118427,229759,252920,712685,490137,101091466,538499,100049986
    Gene Symbol and SynonymsB230206G02Rik,NOE3,NOELIN3,OLFM3,OPTIMEDIN
    Uniprot AccessionQ96PB7,P63057
    Uniprot Entry NameNOE3_HUMAN,NOE3_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000118733
    Target ClassificationN/A

    The target: OLFM3, gene name: OLFM3, also named as NOE3, NOELIN3, OPTIMEDIN. Predicted to be involved in eye photoreceptor cell development. Predicted to be located in Golgi apparatus; extracellular space; and synapse. Predicted to be part of AMPA glutamate receptor complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.