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Anti-OPT/ OPTC functional antibody
Anti-OPT/ OPTC functional antibody for cell culture, ELISA & in-vivo assay
Go to OPTC/OPTC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1158-Ab-1/ GM-Tg-hg-SE1158-Ab-2 | Anti-Human OPTC monoclonal antibody | Human |
| GM-Tg-rg-SE1158-Ab-1/ GM-Tg-rg-SE1158-Ab-2 | Anti-Rat OPTC monoclonal antibody | Rat |
| GM-Tg-mg-SE1158-Ab-1/ GM-Tg-mg-SE1158-Ab-2 | Anti-Mouse OPTC monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1158-Ab-1/ GM-Tg-cynog-SE1158-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OPTC monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1158-Ab-1/ GM-Tg-felg-SE1158-Ab-2 | Anti-Feline OPTC monoclonal antibody | Feline |
| GM-Tg-cang-SE1158-Ab-1/ GM-Tg-cang-SE1158-Ab-2 | Anti-Canine OPTC monoclonal antibody | Canine |
| GM-Tg-bovg-SE1158-Ab-1/ GM-Tg-bovg-SE1158-Ab-2 | Anti-Bovine OPTC monoclonal antibody | Bovine |
| GM-Tg-equg-SE1158-Ab-1/ GM-Tg-equg-SE1158-Ab-2 | Anti-Equine OPTC monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1158-Ab-1/ GM-Tg-hg-SE1158-Ab-2; GM-Tg-rg-SE1158-Ab-1/ GM-Tg-rg-SE1158-Ab-2; GM-Tg-mg-SE1158-Ab-1/ GM-Tg-mg-SE1158-Ab-2; GM-Tg-cynog-SE1158-Ab-1/ GM-Tg-cynog-SE1158-Ab-2; GM-Tg-felg-SE1158-Ab-1/ GM-Tg-felg-SE1158-Ab-2; GM-Tg-cang-SE1158-Ab-1/ GM-Tg-cang-SE1158-Ab-2; GM-Tg-bovg-SE1158-Ab-1/ GM-Tg-bovg-SE1158-Ab-2; GM-Tg-equg-SE1158-Ab-1/ GM-Tg-equg-SE1158-Ab-2 |
| Products Name | Anti-OPTC monoclonal antibody |
| Format | mab |
| Target Name | OPTC |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-OPTC benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1158-Ag-1 | Recombinant multi-species OPT/ OPTC protein |
Target information
| Target ID | GM-SE1158 |
| Target Name | OPTC |
| Gene ID | 26254,269120,304802,702570,403591,101082461,404034,100053612 |
| Gene Symbol and Synonyms | OPT,OPTC,SLRP |
| Uniprot Accession | Q9UBM4,P83286,P58874 |
| Uniprot Entry Name | OPT_HUMAN,OPT_CANLF,OPT_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000188770 |
| Target Classification | N/A |
The target: OPTC, gene name: OPTC, also named as OPT. Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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