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Anti-NEU1/ OXT/ OT functional antibody
Anti-NEU1/ OXT/ OT functional antibody for cell culture, ELISA & in-vivo assay
Go to OXT/OXT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1165-Ab-1/ GM-Tg-hg-SE1165-Ab-2 | Anti-Human OXT monoclonal antibody | Human |
| GM-Tg-rg-SE1165-Ab-1/ GM-Tg-rg-SE1165-Ab-2 | Anti-Rat OXT monoclonal antibody | Rat |
| GM-Tg-mg-SE1165-Ab-1/ GM-Tg-mg-SE1165-Ab-2 | Anti-Mouse OXT monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1165-Ab-1/ GM-Tg-cynog-SE1165-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OXT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1165-Ab-1/ GM-Tg-felg-SE1165-Ab-2 | Anti-Feline OXT monoclonal antibody | Feline |
| GM-Tg-cang-SE1165-Ab-1/ GM-Tg-cang-SE1165-Ab-2 | Anti-Canine OXT monoclonal antibody | Canine |
| GM-Tg-bovg-SE1165-Ab-1/ GM-Tg-bovg-SE1165-Ab-2 | Anti-Bovine OXT monoclonal antibody | Bovine |
| GM-Tg-equg-SE1165-Ab-1/ GM-Tg-equg-SE1165-Ab-2 | Anti-Equine OXT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1165-Ab-1/ GM-Tg-hg-SE1165-Ab-2; GM-Tg-rg-SE1165-Ab-1/ GM-Tg-rg-SE1165-Ab-2; GM-Tg-mg-SE1165-Ab-1/ GM-Tg-mg-SE1165-Ab-2; GM-Tg-cynog-SE1165-Ab-1/ GM-Tg-cynog-SE1165-Ab-2; GM-Tg-felg-SE1165-Ab-1/ GM-Tg-felg-SE1165-Ab-2; GM-Tg-cang-SE1165-Ab-1/ GM-Tg-cang-SE1165-Ab-2; GM-Tg-bovg-SE1165-Ab-1/ GM-Tg-bovg-SE1165-Ab-2; GM-Tg-equg-SE1165-Ab-1/ GM-Tg-equg-SE1165-Ab-2 |
| Products Name | Anti-OXT monoclonal antibody |
| Format | mab |
| Target Name | OXT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-OXT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1165-Ag-1 | Recombinant multi-species NEU1/ OXT/ OT protein |
| ORF Viral Vector | vGMLP004507 | human OXT Lentivirus particle |
| ORF Viral Vector | pGMLP004507 | human OXT Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003740 | mouse Oxt Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003740 | mouse Oxt Lentivirus particle |
Target information
| Target ID | GM-SE1165 |
| Target Name | OXT |
| Gene ID | 5020,18429,25504,717068,100856247,111559702,280888,111767489 |
| Gene Symbol and Synonyms | OT,OT-NPI,OTNPI,OXT,OXT-NPI,Oxy |
| Uniprot Accession | P01178,P01179,P01175 |
| Uniprot Entry Name | NEU1_HUMAN,NEU1_RAT,NEU1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000101405 |
| Target Classification | N/A |
The target: OXT, gene name: OXT, also named as OT, OT-NPI-NPI, OXT. This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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