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Anti-PIBF1/ C13orf24/ CEP90 functional antibody
Anti-PIBF1/ C13orf24/ CEP90 functional antibody for cell culture, ELISA & in-vivo assay
Go to PIBF1/PIBF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1185-Ab-1/ GM-Tg-hg-SE1185-Ab-2 | Anti-Human PIBF1 monoclonal antibody | Human |
| GM-Tg-rg-SE1185-Ab-1/ GM-Tg-rg-SE1185-Ab-2 | Anti-Rat PIBF1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1185-Ab-1/ GM-Tg-mg-SE1185-Ab-2 | Anti-Mouse PIBF1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1185-Ab-1/ GM-Tg-cynog-SE1185-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PIBF1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1185-Ab-1/ GM-Tg-felg-SE1185-Ab-2 | Anti-Feline PIBF1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1185-Ab-1/ GM-Tg-cang-SE1185-Ab-2 | Anti-Canine PIBF1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1185-Ab-1/ GM-Tg-bovg-SE1185-Ab-2 | Anti-Bovine PIBF1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1185-Ab-1/ GM-Tg-equg-SE1185-Ab-2 | Anti-Equine PIBF1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1185-Ab-1/ GM-Tg-hg-SE1185-Ab-2; GM-Tg-rg-SE1185-Ab-1/ GM-Tg-rg-SE1185-Ab-2; GM-Tg-mg-SE1185-Ab-1/ GM-Tg-mg-SE1185-Ab-2; GM-Tg-cynog-SE1185-Ab-1/ GM-Tg-cynog-SE1185-Ab-2; GM-Tg-felg-SE1185-Ab-1/ GM-Tg-felg-SE1185-Ab-2; GM-Tg-cang-SE1185-Ab-1/ GM-Tg-cang-SE1185-Ab-2; GM-Tg-bovg-SE1185-Ab-1/ GM-Tg-bovg-SE1185-Ab-2; GM-Tg-equg-SE1185-Ab-1/ GM-Tg-equg-SE1185-Ab-2 |
| Products Name | Anti-PIBF1 monoclonal antibody |
| Format | mab |
| Target Name | PIBF1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PIBF1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1185-Ag-1 | Recombinant multi-species PIBF1/ C13orf24/ CEP90 protein |
| ORF Viral Vector | pGMLP003932 | human PIBF1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003932 | human PIBF1 Lentivirus particle |
| ORF Viral Vector | pGMLPm004770 | mouse Pibf1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004770 | mouse Pibf1 Lentivirus particle |
Target information
| Target ID | GM-SE1185 |
| Target Name | PIBF1 |
| Gene ID | 10464,52023,306104,694190,476945,101082369,524913,100065926 |
| Gene Symbol and Synonyms | C13orf24,CEP90,JBTS33,PIBF,PIBF1,RGD1305077 |
| Uniprot Accession | Q8WXW3 |
| Uniprot Entry Name | PIBF1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000083535 |
| Target Classification | N/A |
The target: PIBF1, gene name: PIBF1, also named as C13orf24, CEP90, JBTS33, PIBF. This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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