Anti-PROL4/ PRR4/ LPRP functional antibody

Anti-PROL4/ PRR4/ LPRP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PRR4/PRR4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1210-Ab-1/ GM-Tg-hg-SE1210-Ab-2Anti-Human PRR4 monoclonal antibodyHuman
GM-Tg-rg-SE1210-Ab-1/ GM-Tg-rg-SE1210-Ab-2Anti-Rat PRR4 monoclonal antibodyRat
GM-Tg-mg-SE1210-Ab-1/ GM-Tg-mg-SE1210-Ab-2Anti-Mouse PRR4 monoclonal antibodyMouse
GM-Tg-cynog-SE1210-Ab-1/ GM-Tg-cynog-SE1210-Ab-2Anti-Cynomolgus/ Rhesus macaque PRR4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1210-Ab-1/ GM-Tg-felg-SE1210-Ab-2Anti-Feline PRR4 monoclonal antibodyFeline
GM-Tg-cang-SE1210-Ab-1/ GM-Tg-cang-SE1210-Ab-2Anti-Canine PRR4 monoclonal antibodyCanine
GM-Tg-bovg-SE1210-Ab-1/ GM-Tg-bovg-SE1210-Ab-2Anti-Bovine PRR4 monoclonal antibodyBovine
GM-Tg-equg-SE1210-Ab-1/ GM-Tg-equg-SE1210-Ab-2Anti-Equine PRR4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1210-Ab-1/ GM-Tg-hg-SE1210-Ab-2; GM-Tg-rg-SE1210-Ab-1/ GM-Tg-rg-SE1210-Ab-2;
GM-Tg-mg-SE1210-Ab-1/ GM-Tg-mg-SE1210-Ab-2; GM-Tg-cynog-SE1210-Ab-1/ GM-Tg-cynog-SE1210-Ab-2;
GM-Tg-felg-SE1210-Ab-1/ GM-Tg-felg-SE1210-Ab-2; GM-Tg-cang-SE1210-Ab-1/ GM-Tg-cang-SE1210-Ab-2;
GM-Tg-bovg-SE1210-Ab-1/ GM-Tg-bovg-SE1210-Ab-2; GM-Tg-equg-SE1210-Ab-1/ GM-Tg-equg-SE1210-Ab-2
Products NameAnti-PRR4 monoclonal antibody
Formatmab
Target NamePRR4
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRR4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1210-Ag-1Recombinant multi-species PROL4/ PRR4/ LPRP protein


    Target information

    Target IDGM-SE1210
    Target NamePRR4
    Gene ID11272,717988
    Gene Symbol and SynonymsLPRP,PROL4,PRR4
    Uniprot AccessionQ16378
    Uniprot Entry NamePROL4_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000111215
    Target ClassificationN/A

    The target: PRR4, gene name: PRR4, also named as LPRP, PROL4. This gene encodes a member of the proline-rich protein family that lacks a conserved repetitive domain. This protein may play a role in protective functions in the eye. Alternative splicing result in multiple transcript variants. Read-through transcription also exists between this gene and the upstream PRH1 (proline-rich protein HaeIII subfamily 1) gene. [provided by RefSeq, Feb 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.