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Anti-TRY3/ PRSS3/ MTG functional antibody
Anti-TRY3/ PRSS3/ MTG functional antibody for cell culture, ELISA & in-vivo assay
Go to PRSS3/PRSS3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1213-Ab-1/ GM-Tg-hg-SE1213-Ab-2 | Anti-Human PRSS3 monoclonal antibody | Human |
| GM-Tg-rg-SE1213-Ab-1/ GM-Tg-rg-SE1213-Ab-2 | Anti-Rat PRSS3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1213-Ab-1/ GM-Tg-mg-SE1213-Ab-2 | Anti-Mouse PRSS3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1213-Ab-1/ GM-Tg-cynog-SE1213-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRSS3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1213-Ab-1/ GM-Tg-felg-SE1213-Ab-2 | Anti-Feline PRSS3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1213-Ab-1/ GM-Tg-cang-SE1213-Ab-2 | Anti-Canine PRSS3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1213-Ab-1/ GM-Tg-bovg-SE1213-Ab-2 | Anti-Bovine PRSS3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1213-Ab-1/ GM-Tg-equg-SE1213-Ab-2 | Anti-Equine PRSS3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1213-Ab-1/ GM-Tg-hg-SE1213-Ab-2; GM-Tg-rg-SE1213-Ab-1/ GM-Tg-rg-SE1213-Ab-2; GM-Tg-mg-SE1213-Ab-1/ GM-Tg-mg-SE1213-Ab-2; GM-Tg-cynog-SE1213-Ab-1/ GM-Tg-cynog-SE1213-Ab-2; GM-Tg-felg-SE1213-Ab-1/ GM-Tg-felg-SE1213-Ab-2; GM-Tg-cang-SE1213-Ab-1/ GM-Tg-cang-SE1213-Ab-2; GM-Tg-bovg-SE1213-Ab-1/ GM-Tg-bovg-SE1213-Ab-2; GM-Tg-equg-SE1213-Ab-1/ GM-Tg-equg-SE1213-Ab-2 |
| Products Name | Anti-PRSS3 monoclonal antibody |
| Format | mab |
| Target Name | PRSS3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRSS3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1213-Ag-1 | Recombinant multi-species TRY3/ PRSS3/ MTG protein |
| ORF Viral Vector | pGMLP002246 | human PRSS3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002246 | human PRSS3 Lentivirus particle |
| ORF Viral Vector | pGMLPm001218 | mouse Prss3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003753 | mouse Prss3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001218 | mouse Prss3 Lentivirus particle |
| ORF Viral Vector | vGMLPm003753 | mouse Prss3 Lentivirus particle |
Target information
| Target ID | GM-SE1213 |
| Target Name | PRSS3 |
| Gene ID | 5646 |
| Gene Symbol and Synonyms | MTG,PRSS3,PRSS4,T9,TRY3,TRY4 |
| Uniprot Accession | P35030 |
| Uniprot Entry Name | TRY3_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000010438 |
| Target Classification | N/A |
The target: PRSS3, gene name: PRSS3, also named as MTG, PRSS4, T9, TRY3, TRY4. This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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