Anti-PRS37/ PRSS37/ TRYX2 functional antibody

Anti-PRS37/ PRSS37/ TRYX2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PRSS37/PRSS37 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1216-Ab-1/ GM-Tg-hg-SE1216-Ab-2Anti-Human PRSS37 monoclonal antibodyHuman
GM-Tg-rg-SE1216-Ab-1/ GM-Tg-rg-SE1216-Ab-2Anti-Rat PRSS37 monoclonal antibodyRat
GM-Tg-mg-SE1216-Ab-1/ GM-Tg-mg-SE1216-Ab-2Anti-Mouse PRSS37 monoclonal antibodyMouse
GM-Tg-cynog-SE1216-Ab-1/ GM-Tg-cynog-SE1216-Ab-2Anti-Cynomolgus/ Rhesus macaque PRSS37 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1216-Ab-1/ GM-Tg-felg-SE1216-Ab-2Anti-Feline PRSS37 monoclonal antibodyFeline
GM-Tg-cang-SE1216-Ab-1/ GM-Tg-cang-SE1216-Ab-2Anti-Canine PRSS37 monoclonal antibodyCanine
GM-Tg-bovg-SE1216-Ab-1/ GM-Tg-bovg-SE1216-Ab-2Anti-Bovine PRSS37 monoclonal antibodyBovine
GM-Tg-equg-SE1216-Ab-1/ GM-Tg-equg-SE1216-Ab-2Anti-Equine PRSS37 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1216-Ab-1/ GM-Tg-hg-SE1216-Ab-2; GM-Tg-rg-SE1216-Ab-1/ GM-Tg-rg-SE1216-Ab-2;
GM-Tg-mg-SE1216-Ab-1/ GM-Tg-mg-SE1216-Ab-2; GM-Tg-cynog-SE1216-Ab-1/ GM-Tg-cynog-SE1216-Ab-2;
GM-Tg-felg-SE1216-Ab-1/ GM-Tg-felg-SE1216-Ab-2; GM-Tg-cang-SE1216-Ab-1/ GM-Tg-cang-SE1216-Ab-2;
GM-Tg-bovg-SE1216-Ab-1/ GM-Tg-bovg-SE1216-Ab-2; GM-Tg-equg-SE1216-Ab-1/ GM-Tg-equg-SE1216-Ab-2
Products NameAnti-PRSS37 monoclonal antibody
Formatmab
Target NamePRSS37
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRSS37 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1216-Ag-1Recombinant multi-species PRS37/ PRSS37/ TRYX2 protein


    Target information

    Target IDGM-SE1216
    Target NamePRSS37
    Gene ID136242,67690,362346,694908,101083414,540062,100064541
    Gene Symbol and Synonyms1700016G05Rik,PRSS37,RGD1311823,TRYX2
    Uniprot AccessionA4D1T9,Q32KU2
    Uniprot Entry NamePRS37_HUMAN,PRS37_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165076
    Target ClassificationN/A

    The target: PRSS37, gene name: PRSS37, also named as TRYX2. Predicted to enable serine-type endopeptidase activity. Involved in positive regulation of acrosome reaction and regulation of protein processing. Located in acrosomal vesicle. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.