Anti-PRS54/ PRSS54/ CT67 functional antibody

Anti-PRS54/ PRSS54/ CT67 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PRSS54/PRSS54 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1220-Ab-1/ GM-Tg-hg-SE1220-Ab-2Anti-Human PRSS54 monoclonal antibodyHuman
GM-Tg-rg-SE1220-Ab-1/ GM-Tg-rg-SE1220-Ab-2Anti-Rat PRSS54 monoclonal antibodyRat
GM-Tg-mg-SE1220-Ab-1/ GM-Tg-mg-SE1220-Ab-2Anti-Mouse PRSS54 monoclonal antibodyMouse
GM-Tg-cynog-SE1220-Ab-1/ GM-Tg-cynog-SE1220-Ab-2Anti-Cynomolgus/ Rhesus macaque PRSS54 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1220-Ab-1/ GM-Tg-felg-SE1220-Ab-2Anti-Feline PRSS54 monoclonal antibodyFeline
GM-Tg-cang-SE1220-Ab-1/ GM-Tg-cang-SE1220-Ab-2Anti-Canine PRSS54 monoclonal antibodyCanine
GM-Tg-bovg-SE1220-Ab-1/ GM-Tg-bovg-SE1220-Ab-2Anti-Bovine PRSS54 monoclonal antibodyBovine
GM-Tg-equg-SE1220-Ab-1/ GM-Tg-equg-SE1220-Ab-2Anti-Equine PRSS54 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1220-Ab-1/ GM-Tg-hg-SE1220-Ab-2; GM-Tg-rg-SE1220-Ab-1/ GM-Tg-rg-SE1220-Ab-2;
GM-Tg-mg-SE1220-Ab-1/ GM-Tg-mg-SE1220-Ab-2; GM-Tg-cynog-SE1220-Ab-1/ GM-Tg-cynog-SE1220-Ab-2;
GM-Tg-felg-SE1220-Ab-1/ GM-Tg-felg-SE1220-Ab-2; GM-Tg-cang-SE1220-Ab-1/ GM-Tg-cang-SE1220-Ab-2;
GM-Tg-bovg-SE1220-Ab-1/ GM-Tg-bovg-SE1220-Ab-2; GM-Tg-equg-SE1220-Ab-1/ GM-Tg-equg-SE1220-Ab-2
Products NameAnti-PRSS54 monoclonal antibody
Formatmab
Target NamePRSS54
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRSS54 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1220-Ag-1Recombinant multi-species PRS54/ PRSS54/ CT67 protein


    Target information

    Target IDGM-SE1220
    Target NamePRSS54
    Gene ID221191,70993,291846,707045,478107,101093315,529251,100063140
    Gene Symbol and Synonyms4931432M23Rik,CT67,KLKBL4,PRSS54,RGD1307877
    Uniprot AccessionQ6PEW0,Q6AY28
    Uniprot Entry NamePRS54_HUMAN,PRS54_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000103023
    Target ClassificationN/A

    The target: PRSS54, gene name: PRSS54, also named as CT67, KLKBL4. This gene encodes a putative serine-type endopeptidase containing the peptidase S1 domain. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.