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Anti-PRS57/ PRSS57/ NSP4 functional antibody
Anti-PRS57/ PRSS57/ NSP4 functional antibody for cell culture, ELISA & in-vivo assay
Go to PRSS57/PRSS57 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1221-Ab-1/ GM-Tg-hg-SE1221-Ab-2 | Anti-Human PRSS57 monoclonal antibody | Human |
| GM-Tg-rg-SE1221-Ab-1/ GM-Tg-rg-SE1221-Ab-2 | Anti-Rat PRSS57 monoclonal antibody | Rat |
| GM-Tg-mg-SE1221-Ab-1/ GM-Tg-mg-SE1221-Ab-2 | Anti-Mouse PRSS57 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1221-Ab-1/ GM-Tg-cynog-SE1221-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRSS57 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1221-Ab-1/ GM-Tg-felg-SE1221-Ab-2 | Anti-Feline PRSS57 monoclonal antibody | Feline |
| GM-Tg-cang-SE1221-Ab-1/ GM-Tg-cang-SE1221-Ab-2 | Anti-Canine PRSS57 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1221-Ab-1/ GM-Tg-bovg-SE1221-Ab-2 | Anti-Bovine PRSS57 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1221-Ab-1/ GM-Tg-equg-SE1221-Ab-2 | Anti-Equine PRSS57 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1221-Ab-1/ GM-Tg-hg-SE1221-Ab-2; GM-Tg-rg-SE1221-Ab-1/ GM-Tg-rg-SE1221-Ab-2; GM-Tg-mg-SE1221-Ab-1/ GM-Tg-mg-SE1221-Ab-2; GM-Tg-cynog-SE1221-Ab-1/ GM-Tg-cynog-SE1221-Ab-2; GM-Tg-felg-SE1221-Ab-1/ GM-Tg-felg-SE1221-Ab-2; GM-Tg-cang-SE1221-Ab-1/ GM-Tg-cang-SE1221-Ab-2; GM-Tg-bovg-SE1221-Ab-1/ GM-Tg-bovg-SE1221-Ab-2; GM-Tg-equg-SE1221-Ab-1/ GM-Tg-equg-SE1221-Ab-2 |
| Products Name | Anti-PRSS57 monoclonal antibody |
| Format | mab |
| Target Name | PRSS57 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRSS57 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1221-Ag-1 | Recombinant multi-species PRS57/ PRSS57/ NSP4 protein |
| ORF Viral Vector | vGMLP004727 | human NSP4 Lentivirus particle |
| ORF Viral Vector | pGMLP004727 | human NSP4 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003520 | mouse Prss57 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003520 | mouse Prss57 Lentivirus particle |
Target information
| Target ID | GM-SE1221 |
| Target Name | PRSS57 |
| Gene ID | 400668,73106,408241,721106,485099,101092003,515368,102147643 |
| Gene Symbol and Synonyms | 2900092M14Rik,Df2,GLGL782,NSP4,PRSS57,PRSSL1,UNQ782 |
| Uniprot Accession | Q6UWY2,Q6IE59 |
| Uniprot Entry Name | PRS57_HUMAN,PRS57_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000185198 |
| Target Classification | N/A |
The target: PRSS57, gene name: PRSS57, also named as NSP4, PRSSL1, UNQ782. This gene encodes an arginine-specific serine protease and member of the peptidase S1 family of proteins. The encoded protein may undergo proteolytic activation before storage in azurophil granules, in neutrophil cells of the immune system. Following neutrophil activation, the protease is released into the pericellular environment, where it may play a role in defense against microbial pathogens. [provided by RefSeq, Jul 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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