Anti-PRS58/ PRSS58/ PRSS1 functional antibody

Anti-PRS58/ PRSS58/ PRSS1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PRSS58/PRSS58 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1222-Ab-1/ GM-Tg-hg-SE1222-Ab-2Anti-Human PRSS58 monoclonal antibodyHuman
GM-Tg-rg-SE1222-Ab-1/ GM-Tg-rg-SE1222-Ab-2Anti-Rat PRSS58 monoclonal antibodyRat
GM-Tg-mg-SE1222-Ab-1/ GM-Tg-mg-SE1222-Ab-2Anti-Mouse PRSS58 monoclonal antibodyMouse
GM-Tg-cynog-SE1222-Ab-1/ GM-Tg-cynog-SE1222-Ab-2Anti-Cynomolgus/ Rhesus macaque PRSS58 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1222-Ab-1/ GM-Tg-felg-SE1222-Ab-2Anti-Feline PRSS58 monoclonal antibodyFeline
GM-Tg-cang-SE1222-Ab-1/ GM-Tg-cang-SE1222-Ab-2Anti-Canine PRSS58 monoclonal antibodyCanine
GM-Tg-bovg-SE1222-Ab-1/ GM-Tg-bovg-SE1222-Ab-2Anti-Bovine PRSS58 monoclonal antibodyBovine
GM-Tg-equg-SE1222-Ab-1/ GM-Tg-equg-SE1222-Ab-2Anti-Equine PRSS58 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1222-Ab-1/ GM-Tg-hg-SE1222-Ab-2; GM-Tg-rg-SE1222-Ab-1/ GM-Tg-rg-SE1222-Ab-2;
GM-Tg-mg-SE1222-Ab-1/ GM-Tg-mg-SE1222-Ab-2; GM-Tg-cynog-SE1222-Ab-1/ GM-Tg-cynog-SE1222-Ab-2;
GM-Tg-felg-SE1222-Ab-1/ GM-Tg-felg-SE1222-Ab-2; GM-Tg-cang-SE1222-Ab-1/ GM-Tg-cang-SE1222-Ab-2;
GM-Tg-bovg-SE1222-Ab-1/ GM-Tg-bovg-SE1222-Ab-2; GM-Tg-equg-SE1222-Ab-1/ GM-Tg-equg-SE1222-Ab-2
Products NameAnti-PRSS58 monoclonal antibody
Formatmab
Target NamePRSS58
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRSS58 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1222-Ag-1Recombinant multi-species PRS58/ PRSS58/ PRSS1 protein


    Target information

    Target IDGM-SE1222
    Target NamePRSS58
    Gene ID136541,232717,408204,696251
    Gene Symbol and Synonyms1700020H15,PRSS1,PRSS58,TRY1,TRYX3,UNQ2540
    Uniprot AccessionQ8IYP2,Q6IE06
    Uniprot Entry NamePRS58_HUMAN,PRS58_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000258223
    Target ClassificationN/A

    The target: PRSS58, gene name: PRSS58, also named as PRSS1, TRY1, TRYX3, UNQ2540. This gene encodes a member of the trypsin family of serine proteases. This gene and several related trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. This gene was previously described as a trypsinogen-like pseudogene, but it is now thought to be a protein-coding gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.