Anti-PSG11/ PSBG-11/ PSBG-13 functional antibody

Anti-PSG11/ PSBG-11/ PSBG-13 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PSG11/PSG11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1224-Ab-1/ GM-Tg-hg-SE1224-Ab-2Anti-Human PSG11 monoclonal antibodyHuman
GM-Tg-rg-SE1224-Ab-1/ GM-Tg-rg-SE1224-Ab-2Anti-Rat PSG11 monoclonal antibodyRat
GM-Tg-mg-SE1224-Ab-1/ GM-Tg-mg-SE1224-Ab-2Anti-Mouse PSG11 monoclonal antibodyMouse
GM-Tg-cynog-SE1224-Ab-1/ GM-Tg-cynog-SE1224-Ab-2Anti-Cynomolgus/ Rhesus macaque PSG11 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1224-Ab-1/ GM-Tg-felg-SE1224-Ab-2Anti-Feline PSG11 monoclonal antibodyFeline
GM-Tg-cang-SE1224-Ab-1/ GM-Tg-cang-SE1224-Ab-2Anti-Canine PSG11 monoclonal antibodyCanine
GM-Tg-bovg-SE1224-Ab-1/ GM-Tg-bovg-SE1224-Ab-2Anti-Bovine PSG11 monoclonal antibodyBovine
GM-Tg-equg-SE1224-Ab-1/ GM-Tg-equg-SE1224-Ab-2Anti-Equine PSG11 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1224-Ab-1/ GM-Tg-hg-SE1224-Ab-2; GM-Tg-rg-SE1224-Ab-1/ GM-Tg-rg-SE1224-Ab-2;
GM-Tg-mg-SE1224-Ab-1/ GM-Tg-mg-SE1224-Ab-2; GM-Tg-cynog-SE1224-Ab-1/ GM-Tg-cynog-SE1224-Ab-2;
GM-Tg-felg-SE1224-Ab-1/ GM-Tg-felg-SE1224-Ab-2; GM-Tg-cang-SE1224-Ab-1/ GM-Tg-cang-SE1224-Ab-2;
GM-Tg-bovg-SE1224-Ab-1/ GM-Tg-bovg-SE1224-Ab-2; GM-Tg-equg-SE1224-Ab-1/ GM-Tg-equg-SE1224-Ab-2
Products NameAnti-PSG11 monoclonal antibody
Formatmab
Target NamePSG11
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PSG11 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1224-Ag-1Recombinant multi-species PSG11/ PSBG-11/ PSBG-13 protein


    Target information

    Target IDGM-SE1224
    Target NamePSG11
    Gene ID5680
    Gene Symbol and SynonymsPSBG-11,PSBG-13,PSG11,PSG13,PSG14
    Uniprot AccessionQ9UQ72
    Uniprot Entry NamePSG11_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000243130
    Target ClassificationN/A

    The target: PSG11, gene name: PSG11, also named as PSBG-11, PSBG-13, PSG13, PSG14. The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.