Anti-CRSPL/ R3HDML/ dJ881L22.3 functional antibody

Anti-CRSPL/ R3HDML/ dJ881L22.3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to R3HDML/R3HDML products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1233-Ab-1/ GM-Tg-hg-SE1233-Ab-2Anti-Human R3HDML monoclonal antibodyHuman
GM-Tg-rg-SE1233-Ab-1/ GM-Tg-rg-SE1233-Ab-2Anti-Rat R3HDML monoclonal antibodyRat
GM-Tg-mg-SE1233-Ab-1/ GM-Tg-mg-SE1233-Ab-2Anti-Mouse R3HDML monoclonal antibodyMouse
GM-Tg-cynog-SE1233-Ab-1/ GM-Tg-cynog-SE1233-Ab-2Anti-Cynomolgus/ Rhesus macaque R3HDML monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1233-Ab-1/ GM-Tg-felg-SE1233-Ab-2Anti-Feline R3HDML monoclonal antibodyFeline
GM-Tg-cang-SE1233-Ab-1/ GM-Tg-cang-SE1233-Ab-2Anti-Canine R3HDML monoclonal antibodyCanine
GM-Tg-bovg-SE1233-Ab-1/ GM-Tg-bovg-SE1233-Ab-2Anti-Bovine R3HDML monoclonal antibodyBovine
GM-Tg-equg-SE1233-Ab-1/ GM-Tg-equg-SE1233-Ab-2Anti-Equine R3HDML monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1233-Ab-1/ GM-Tg-hg-SE1233-Ab-2; GM-Tg-rg-SE1233-Ab-1/ GM-Tg-rg-SE1233-Ab-2;
GM-Tg-mg-SE1233-Ab-1/ GM-Tg-mg-SE1233-Ab-2; GM-Tg-cynog-SE1233-Ab-1/ GM-Tg-cynog-SE1233-Ab-2;
GM-Tg-felg-SE1233-Ab-1/ GM-Tg-felg-SE1233-Ab-2; GM-Tg-cang-SE1233-Ab-1/ GM-Tg-cang-SE1233-Ab-2;
GM-Tg-bovg-SE1233-Ab-1/ GM-Tg-bovg-SE1233-Ab-2; GM-Tg-equg-SE1233-Ab-1/ GM-Tg-equg-SE1233-Ab-2
Products NameAnti-R3HDML monoclonal antibody
Formatmab
Target NameR3HDML
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-R3HDML benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1233-Ag-1Recombinant multi-species CRSPL/ R3HDML/ dJ881L22.3 protein


    Target information

    Target IDGM-SE1233
    Target NameR3HDML
    Gene ID140902,100043899,366245,693511,485883,101093263,533734,100147026
    Gene Symbol and SynonymsdJ881L22.3,R3HDML
    Uniprot AccessionQ9H3Y0
    Uniprot Entry NameCRSPL_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000101074
    Target ClassificationN/A

    The target: R3HDML, gene name: R3HDML, also named as dJ881L22.3. Predicted to enable peptidase inhibitor activity. Predicted to be involved in negative regulation of peptidase activity. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.