Anti-REG3G/ LPPM429/ PAP IB functional antibody

Anti-REG3G/ LPPM429/ PAP IB functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to REG3G/REG3G products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1238-Ab-1/ GM-Tg-hg-SE1238-Ab-2Anti-Human REG3G monoclonal antibodyHuman
GM-Tg-rg-SE1238-Ab-1/ GM-Tg-rg-SE1238-Ab-2Anti-Rat REG3G monoclonal antibodyRat
GM-Tg-mg-SE1238-Ab-1/ GM-Tg-mg-SE1238-Ab-2Anti-Mouse REG3G monoclonal antibodyMouse
GM-Tg-cynog-SE1238-Ab-1/ GM-Tg-cynog-SE1238-Ab-2Anti-Cynomolgus/ Rhesus macaque REG3G monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1238-Ab-1/ GM-Tg-felg-SE1238-Ab-2Anti-Feline REG3G monoclonal antibodyFeline
GM-Tg-cang-SE1238-Ab-1/ GM-Tg-cang-SE1238-Ab-2Anti-Canine REG3G monoclonal antibodyCanine
GM-Tg-bovg-SE1238-Ab-1/ GM-Tg-bovg-SE1238-Ab-2Anti-Bovine REG3G monoclonal antibodyBovine
GM-Tg-equg-SE1238-Ab-1/ GM-Tg-equg-SE1238-Ab-2Anti-Equine REG3G monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1238-Ab-1/ GM-Tg-hg-SE1238-Ab-2; GM-Tg-rg-SE1238-Ab-1/ GM-Tg-rg-SE1238-Ab-2;
GM-Tg-mg-SE1238-Ab-1/ GM-Tg-mg-SE1238-Ab-2; GM-Tg-cynog-SE1238-Ab-1/ GM-Tg-cynog-SE1238-Ab-2;
GM-Tg-felg-SE1238-Ab-1/ GM-Tg-felg-SE1238-Ab-2; GM-Tg-cang-SE1238-Ab-1/ GM-Tg-cang-SE1238-Ab-2;
GM-Tg-bovg-SE1238-Ab-1/ GM-Tg-bovg-SE1238-Ab-2; GM-Tg-equg-SE1238-Ab-1/ GM-Tg-equg-SE1238-Ab-2
Products NameAnti-REG3G monoclonal antibody
Formatmab
Target NameREG3G
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-REG3G benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1238-Ag-1Recombinant multi-species REG3G/ LPPM429/ PAP IB protein


    Target information

    Target IDGM-SE1238
    Target NameREG3G
    Gene ID130120,711637
    Gene Symbol and SynonymsLPPM429,PAP IB,PAP-1B,PAP1B,PAPIB,REG III,REG-III,REG3G,UNQ429
    Uniprot AccessionQ6UW15
    Uniprot Entry NameREG3G_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000143954
    Target ClassificationN/A

    The target: REG3G, gene name: REG3G, also named as LPPM429, PAP IB, PAP-1B, PAP1B, PAPIB, REG III, REG-III, UNQ429. This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antimicrobial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Nov 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.