Anti-RNAS2/ RNASE2/ EDN functional antibody

Anti-RNAS2/ RNASE2/ EDN functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to RNASE2/RNASE2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1247-Ab-1/ GM-Tg-hg-SE1247-Ab-2Anti-Human RNASE2 monoclonal antibodyHuman
GM-Tg-rg-SE1247-Ab-1/ GM-Tg-rg-SE1247-Ab-2Anti-Rat RNASE2 monoclonal antibodyRat
GM-Tg-mg-SE1247-Ab-1/ GM-Tg-mg-SE1247-Ab-2Anti-Mouse RNASE2 monoclonal antibodyMouse
GM-Tg-cynog-SE1247-Ab-1/ GM-Tg-cynog-SE1247-Ab-2Anti-Cynomolgus/ Rhesus macaque RNASE2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1247-Ab-1/ GM-Tg-felg-SE1247-Ab-2Anti-Feline RNASE2 monoclonal antibodyFeline
GM-Tg-cang-SE1247-Ab-1/ GM-Tg-cang-SE1247-Ab-2Anti-Canine RNASE2 monoclonal antibodyCanine
GM-Tg-bovg-SE1247-Ab-1/ GM-Tg-bovg-SE1247-Ab-2Anti-Bovine RNASE2 monoclonal antibodyBovine
GM-Tg-equg-SE1247-Ab-1/ GM-Tg-equg-SE1247-Ab-2Anti-Equine RNASE2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1247-Ab-1/ GM-Tg-hg-SE1247-Ab-2; GM-Tg-rg-SE1247-Ab-1/ GM-Tg-rg-SE1247-Ab-2;
GM-Tg-mg-SE1247-Ab-1/ GM-Tg-mg-SE1247-Ab-2; GM-Tg-cynog-SE1247-Ab-1/ GM-Tg-cynog-SE1247-Ab-2;
GM-Tg-felg-SE1247-Ab-1/ GM-Tg-felg-SE1247-Ab-2; GM-Tg-cang-SE1247-Ab-1/ GM-Tg-cang-SE1247-Ab-2;
GM-Tg-bovg-SE1247-Ab-1/ GM-Tg-bovg-SE1247-Ab-2; GM-Tg-equg-SE1247-Ab-1/ GM-Tg-equg-SE1247-Ab-2
Products NameAnti-RNASE2 monoclonal antibody
Formatmab
Target NameRNASE2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RNASE2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1247-Ag-1Recombinant multi-species RNAS2/ RNASE2/ EDN protein


    Target information

    Target IDGM-SE1247
    Target NameRNASE2
    Gene ID6036,93719,706466,100125948
    Gene Symbol and SynonymsEar6,EDN,RAF3,RNASE2,RNASE3,RNS2
    Uniprot AccessionP10153
    Uniprot Entry NameRNAS2_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169385
    Target ClassificationN/A

    The target: RNASE2, gene name: RNASE2, also named as EDN, RAF3, RNS2. The protein encoded by this gene is a non-secretory ribonuclease that belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein antimicrobial activity against viruses. [provided by RefSeq, Oct 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.