Anti-RSPRY/ RSPRY1/ SEMDFA functional antibody

Anti-RSPRY/ RSPRY1/ SEMDFA functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to RSPRY1/RSPRY1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1256-Ab-1/ GM-Tg-hg-SE1256-Ab-2Anti-Human RSPRY1 monoclonal antibodyHuman
GM-Tg-rg-SE1256-Ab-1/ GM-Tg-rg-SE1256-Ab-2Anti-Rat RSPRY1 monoclonal antibodyRat
GM-Tg-mg-SE1256-Ab-1/ GM-Tg-mg-SE1256-Ab-2Anti-Mouse RSPRY1 monoclonal antibodyMouse
GM-Tg-cynog-SE1256-Ab-1/ GM-Tg-cynog-SE1256-Ab-2Anti-Cynomolgus/ Rhesus macaque RSPRY1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1256-Ab-1/ GM-Tg-felg-SE1256-Ab-2Anti-Feline RSPRY1 monoclonal antibodyFeline
GM-Tg-cang-SE1256-Ab-1/ GM-Tg-cang-SE1256-Ab-2Anti-Canine RSPRY1 monoclonal antibodyCanine
GM-Tg-bovg-SE1256-Ab-1/ GM-Tg-bovg-SE1256-Ab-2Anti-Bovine RSPRY1 monoclonal antibodyBovine
GM-Tg-equg-SE1256-Ab-1/ GM-Tg-equg-SE1256-Ab-2Anti-Equine RSPRY1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1256-Ab-1/ GM-Tg-hg-SE1256-Ab-2; GM-Tg-rg-SE1256-Ab-1/ GM-Tg-rg-SE1256-Ab-2;
GM-Tg-mg-SE1256-Ab-1/ GM-Tg-mg-SE1256-Ab-2; GM-Tg-cynog-SE1256-Ab-1/ GM-Tg-cynog-SE1256-Ab-2;
GM-Tg-felg-SE1256-Ab-1/ GM-Tg-felg-SE1256-Ab-2; GM-Tg-cang-SE1256-Ab-1/ GM-Tg-cang-SE1256-Ab-2;
GM-Tg-bovg-SE1256-Ab-1/ GM-Tg-bovg-SE1256-Ab-2; GM-Tg-equg-SE1256-Ab-1/ GM-Tg-equg-SE1256-Ab-2
Products NameAnti-RSPRY1 monoclonal antibody
Formatmab
Target NameRSPRY1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RSPRY1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1256-Ag-1Recombinant multi-species RSPRY/ RSPRY1/ SEMDFA protein
    ORF Viral VectorpGMLPm005084mouse Rspry1 Lentivirus plasmid
    ORF Viral VectorvGMLPm005084mouse Rspry1 Lentivirus particle


    Target information

    Target IDGM-SE1256
    Target NameRSPRY1
    Gene ID89970,67610,689249,703783,478112,101083894,538571,100052133
    Gene Symbol and Synonyms4930470D19Rik,RGD1308847,RSPRY1,SEMDFA
    Uniprot AccessionQ96DX4
    Uniprot Entry NameRSPRY_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000159579
    Target ClassificationN/A

    The target: RSPRY1, gene name: RSPRY1, also named as SEMDFA. This gene encodes a glycoprotein that contains a RING-type zinc finger domain and an SPRY domain of unknown function. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.