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Anti-SAA2/ SAA/ SAA1 functional antibody
Anti-SAA2/ SAA/ SAA1 functional antibody for cell culture, ELISA & in-vivo assay
Go to SAA2/SAA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1258-Ab-1/ GM-Tg-hg-SE1258-Ab-2 | Anti-Human SAA2 monoclonal antibody | Human |
| GM-Tg-rg-SE1258-Ab-1/ GM-Tg-rg-SE1258-Ab-2 | Anti-Rat SAA2 monoclonal antibody | Rat |
| GM-Tg-mg-SE1258-Ab-1/ GM-Tg-mg-SE1258-Ab-2 | Anti-Mouse SAA2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1258-Ab-1/ GM-Tg-cynog-SE1258-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SAA2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1258-Ab-1/ GM-Tg-felg-SE1258-Ab-2 | Anti-Feline SAA2 monoclonal antibody | Feline |
| GM-Tg-cang-SE1258-Ab-1/ GM-Tg-cang-SE1258-Ab-2 | Anti-Canine SAA2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1258-Ab-1/ GM-Tg-bovg-SE1258-Ab-2 | Anti-Bovine SAA2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1258-Ab-1/ GM-Tg-equg-SE1258-Ab-2 | Anti-Equine SAA2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1258-Ab-1/ GM-Tg-hg-SE1258-Ab-2; GM-Tg-rg-SE1258-Ab-1/ GM-Tg-rg-SE1258-Ab-2; GM-Tg-mg-SE1258-Ab-1/ GM-Tg-mg-SE1258-Ab-2; GM-Tg-cynog-SE1258-Ab-1/ GM-Tg-cynog-SE1258-Ab-2; GM-Tg-felg-SE1258-Ab-1/ GM-Tg-felg-SE1258-Ab-2; GM-Tg-cang-SE1258-Ab-1/ GM-Tg-cang-SE1258-Ab-2; GM-Tg-bovg-SE1258-Ab-1/ GM-Tg-bovg-SE1258-Ab-2; GM-Tg-equg-SE1258-Ab-1/ GM-Tg-equg-SE1258-Ab-2 |
| Products Name | Anti-SAA2 monoclonal antibody |
| Format | mab |
| Target Name | SAA2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SAA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1258-Ag-1 | Recombinant multi-species SAA2/ SAA/ SAA1 protein |
| ORF Viral Vector | pGMLP003394 | human SAA2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003394 | human SAA2 Lentivirus particle |
| ORF Viral Vector | pGMLPm000199 | mouse Saa2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000199 | mouse Saa2 Lentivirus particle |
Target information
| Target ID | GM-SE1258 |
| Target Name | SAA2 |
| Gene ID | 6289,694827 |
| Gene Symbol and Synonyms | SAA,SAA1,SAA2 |
| Uniprot Accession | P0DJI9 |
| Uniprot Entry Name | SAA2_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000134339 |
| Target Classification | N/A |
The target: SAA2, gene name: SAA2, also named as SAA, SAA1. This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. [provided by RefSeq, Jul 2020].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
