Anti-SG2A1/ SCGB2A1/ LPHC functional antibody

Anti-SG2A1/ SCGB2A1/ LPHC functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SCGB2A1/SCGB2A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1267-Ab-1/ GM-Tg-hg-SE1267-Ab-2Anti-Human SCGB2A1 monoclonal antibodyHuman
GM-Tg-rg-SE1267-Ab-1/ GM-Tg-rg-SE1267-Ab-2Anti-Rat SCGB2A1 monoclonal antibodyRat
GM-Tg-mg-SE1267-Ab-1/ GM-Tg-mg-SE1267-Ab-2Anti-Mouse SCGB2A1 monoclonal antibodyMouse
GM-Tg-cynog-SE1267-Ab-1/ GM-Tg-cynog-SE1267-Ab-2Anti-Cynomolgus/ Rhesus macaque SCGB2A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1267-Ab-1/ GM-Tg-felg-SE1267-Ab-2Anti-Feline SCGB2A1 monoclonal antibodyFeline
GM-Tg-cang-SE1267-Ab-1/ GM-Tg-cang-SE1267-Ab-2Anti-Canine SCGB2A1 monoclonal antibodyCanine
GM-Tg-bovg-SE1267-Ab-1/ GM-Tg-bovg-SE1267-Ab-2Anti-Bovine SCGB2A1 monoclonal antibodyBovine
GM-Tg-equg-SE1267-Ab-1/ GM-Tg-equg-SE1267-Ab-2Anti-Equine SCGB2A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1267-Ab-1/ GM-Tg-hg-SE1267-Ab-2; GM-Tg-rg-SE1267-Ab-1/ GM-Tg-rg-SE1267-Ab-2;
GM-Tg-mg-SE1267-Ab-1/ GM-Tg-mg-SE1267-Ab-2; GM-Tg-cynog-SE1267-Ab-1/ GM-Tg-cynog-SE1267-Ab-2;
GM-Tg-felg-SE1267-Ab-1/ GM-Tg-felg-SE1267-Ab-2; GM-Tg-cang-SE1267-Ab-1/ GM-Tg-cang-SE1267-Ab-2;
GM-Tg-bovg-SE1267-Ab-1/ GM-Tg-bovg-SE1267-Ab-2; GM-Tg-equg-SE1267-Ab-1/ GM-Tg-equg-SE1267-Ab-2
Products NameAnti-SCGB2A1 monoclonal antibody
Formatmab
Target NameSCGB2A1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SCGB2A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1267-Ag-1Recombinant multi-species SG2A1/ SCGB2A1/ LPHC protein


    Target information

    Target IDGM-SE1267
    Target NameSCGB2A1
    Gene ID4246,361725
    Gene Symbol and SynonymsC3.1,LPHC,LPNC,MGB2,Psbp1,Psbpc3,SCGB2A1,Scgb2a2,UGB3
    Uniprot AccessionO75556,P02780,Q9JHB9
    Uniprot Entry NameSG2A1_HUMAN,SG2A2_RAT,SG2A1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseBreast Cancer, Prostate Cancer
    Gene EnsemblENSG00000124939
    Target ClassificationN/A

    The target: SCGB2A1, gene name: SCGB2A1, also named as LPHC, LPNC, MGB2, UGB3. Involved in androgen receptor signaling pathway. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.