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Anti-SEM3F/ SEMA3F/ SEMA-IV functional antibody
Anti-SEM3F/ SEMA3F/ SEMA-IV functional antibody for cell culture, ELISA & in-vivo assay
Go to SEMA3F/SEMA3F products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1273-Ab-1/ GM-Tg-hg-SE1273-Ab-2 | Anti-Human SEMA3F monoclonal antibody | Human |
| GM-Tg-rg-SE1273-Ab-1/ GM-Tg-rg-SE1273-Ab-2 | Anti-Rat SEMA3F monoclonal antibody | Rat |
| GM-Tg-mg-SE1273-Ab-1/ GM-Tg-mg-SE1273-Ab-2 | Anti-Mouse SEMA3F monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1273-Ab-1/ GM-Tg-cynog-SE1273-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SEMA3F monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1273-Ab-1/ GM-Tg-felg-SE1273-Ab-2 | Anti-Feline SEMA3F monoclonal antibody | Feline |
| GM-Tg-cang-SE1273-Ab-1/ GM-Tg-cang-SE1273-Ab-2 | Anti-Canine SEMA3F monoclonal antibody | Canine |
| GM-Tg-bovg-SE1273-Ab-1/ GM-Tg-bovg-SE1273-Ab-2 | Anti-Bovine SEMA3F monoclonal antibody | Bovine |
| GM-Tg-equg-SE1273-Ab-1/ GM-Tg-equg-SE1273-Ab-2 | Anti-Equine SEMA3F monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1273-Ab-1/ GM-Tg-hg-SE1273-Ab-2; GM-Tg-rg-SE1273-Ab-1/ GM-Tg-rg-SE1273-Ab-2; GM-Tg-mg-SE1273-Ab-1/ GM-Tg-mg-SE1273-Ab-2; GM-Tg-cynog-SE1273-Ab-1/ GM-Tg-cynog-SE1273-Ab-2; GM-Tg-felg-SE1273-Ab-1/ GM-Tg-felg-SE1273-Ab-2; GM-Tg-cang-SE1273-Ab-1/ GM-Tg-cang-SE1273-Ab-2; GM-Tg-bovg-SE1273-Ab-1/ GM-Tg-bovg-SE1273-Ab-2; GM-Tg-equg-SE1273-Ab-1/ GM-Tg-equg-SE1273-Ab-2 |
| Products Name | Anti-SEMA3F monoclonal antibody |
| Format | mab |
| Target Name | SEMA3F |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SEMA3F benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1273-Ag-1 | Recombinant multi-species SEM3F/ SEMA3F/ SEMA-IV protein |
Target information
| Target ID | GM-SE1273 |
| Target Name | SEMA3F |
| Gene ID | 6405,20350,315996,703995,484763,101091515,531141,100062215 |
| Gene Symbol and Synonyms | SEMA-IV,SEMA3F,SEMA4,SemaIV,SEMAK |
| Uniprot Accession | Q13275 |
| Uniprot Entry Name | SEM3F_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000001617 |
| Target Classification | N/A |
The target: SEMA3F, gene name: SEMA3F, also named as SEMA-IV, SEMA4, SEMAK. This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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