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Anti-SEMG1/ CT103/ SEMG functional antibody
Anti-SEMG1/ CT103/ SEMG functional antibody for cell culture, ELISA & in-vivo assay
Go to SEMG1/SEMG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1275-Ab-1/ GM-Tg-hg-SE1275-Ab-2 | Anti-Human SEMG1 monoclonal antibody | Human |
| GM-Tg-rg-SE1275-Ab-1/ GM-Tg-rg-SE1275-Ab-2 | Anti-Rat SEMG1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1275-Ab-1/ GM-Tg-mg-SE1275-Ab-2 | Anti-Mouse SEMG1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1275-Ab-1/ GM-Tg-cynog-SE1275-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SEMG1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1275-Ab-1/ GM-Tg-felg-SE1275-Ab-2 | Anti-Feline SEMG1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1275-Ab-1/ GM-Tg-cang-SE1275-Ab-2 | Anti-Canine SEMG1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1275-Ab-1/ GM-Tg-bovg-SE1275-Ab-2 | Anti-Bovine SEMG1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1275-Ab-1/ GM-Tg-equg-SE1275-Ab-2 | Anti-Equine SEMG1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1275-Ab-1/ GM-Tg-hg-SE1275-Ab-2; GM-Tg-rg-SE1275-Ab-1/ GM-Tg-rg-SE1275-Ab-2; GM-Tg-mg-SE1275-Ab-1/ GM-Tg-mg-SE1275-Ab-2; GM-Tg-cynog-SE1275-Ab-1/ GM-Tg-cynog-SE1275-Ab-2; GM-Tg-felg-SE1275-Ab-1/ GM-Tg-felg-SE1275-Ab-2; GM-Tg-cang-SE1275-Ab-1/ GM-Tg-cang-SE1275-Ab-2; GM-Tg-bovg-SE1275-Ab-1/ GM-Tg-bovg-SE1275-Ab-2; GM-Tg-equg-SE1275-Ab-1/ GM-Tg-equg-SE1275-Ab-2 |
| Products Name | Anti-SEMG1 monoclonal antibody |
| Format | mab |
| Target Name | SEMG1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SEMG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1275-Ag-1 | Recombinant multi-species SEMG1/ CT103/ SEMG protein |
Target information
| Target ID | GM-SE1275 |
| Target Name | SEMG1 |
| Gene ID | 6406 |
| Gene Symbol and Synonyms | CT103,dJ172H20.2,SEMG,SEMG1,SGI |
| Uniprot Accession | P04279 |
| Uniprot Entry Name | SEMG1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Contrast - Induced Nephropathy, Malignant neoplasm of bladder |
| Gene Ensembl | ENSG00000124233 |
| Target Classification | N/A |
The target: SEMG1, gene name: SEMG1, also named as CT103, SEMG, SGI, dJ172H20.2. The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20. [provided by RefSeq, Feb 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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