Anti-SEMG2/ SGII functional antibody

Anti-SEMG2/ SGII functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SEMG2/SEMG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1276-Ab-1/ GM-Tg-hg-SE1276-Ab-2Anti-Human SEMG2 monoclonal antibodyHuman
GM-Tg-rg-SE1276-Ab-1/ GM-Tg-rg-SE1276-Ab-2Anti-Rat SEMG2 monoclonal antibodyRat
GM-Tg-mg-SE1276-Ab-1/ GM-Tg-mg-SE1276-Ab-2Anti-Mouse SEMG2 monoclonal antibodyMouse
GM-Tg-cynog-SE1276-Ab-1/ GM-Tg-cynog-SE1276-Ab-2Anti-Cynomolgus/ Rhesus macaque SEMG2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1276-Ab-1/ GM-Tg-felg-SE1276-Ab-2Anti-Feline SEMG2 monoclonal antibodyFeline
GM-Tg-cang-SE1276-Ab-1/ GM-Tg-cang-SE1276-Ab-2Anti-Canine SEMG2 monoclonal antibodyCanine
GM-Tg-bovg-SE1276-Ab-1/ GM-Tg-bovg-SE1276-Ab-2Anti-Bovine SEMG2 monoclonal antibodyBovine
GM-Tg-equg-SE1276-Ab-1/ GM-Tg-equg-SE1276-Ab-2Anti-Equine SEMG2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1276-Ab-1/ GM-Tg-hg-SE1276-Ab-2; GM-Tg-rg-SE1276-Ab-1/ GM-Tg-rg-SE1276-Ab-2;
GM-Tg-mg-SE1276-Ab-1/ GM-Tg-mg-SE1276-Ab-2; GM-Tg-cynog-SE1276-Ab-1/ GM-Tg-cynog-SE1276-Ab-2;
GM-Tg-felg-SE1276-Ab-1/ GM-Tg-felg-SE1276-Ab-2; GM-Tg-cang-SE1276-Ab-1/ GM-Tg-cang-SE1276-Ab-2;
GM-Tg-bovg-SE1276-Ab-1/ GM-Tg-bovg-SE1276-Ab-2; GM-Tg-equg-SE1276-Ab-1/ GM-Tg-equg-SE1276-Ab-2
Products NameAnti-SEMG2 monoclonal antibody
Formatmab
Target NameSEMG2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SEMG2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1276-Ag-1Recombinant multi-species SEMG2/ SGII protein


    Target information

    Target IDGM-SE1276
    Target NameSEMG2
    Gene ID6407,711317
    Gene Symbol and SynonymsSEMG2,SGII
    Uniprot AccessionQ02383,Q95196
    Uniprot Entry NameSEMG2_HUMAN,SEMG2_MACMU
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000124157
    Target ClassificationN/A

    The target: SEMG2, gene name: SEMG2, also named as SGII. The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.