Anti-SNED1/ IRE-BP1/ SST3 functional antibody

Anti-SNED1/ IRE-BP1/ SST3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SNED1/SNED1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1298-Ab-1/ GM-Tg-hg-SE1298-Ab-2Anti-Human SNED1 monoclonal antibodyHuman
GM-Tg-rg-SE1298-Ab-1/ GM-Tg-rg-SE1298-Ab-2Anti-Rat SNED1 monoclonal antibodyRat
GM-Tg-mg-SE1298-Ab-1/ GM-Tg-mg-SE1298-Ab-2Anti-Mouse SNED1 monoclonal antibodyMouse
GM-Tg-cynog-SE1298-Ab-1/ GM-Tg-cynog-SE1298-Ab-2Anti-Cynomolgus/ Rhesus macaque SNED1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1298-Ab-1/ GM-Tg-felg-SE1298-Ab-2Anti-Feline SNED1 monoclonal antibodyFeline
GM-Tg-cang-SE1298-Ab-1/ GM-Tg-cang-SE1298-Ab-2Anti-Canine SNED1 monoclonal antibodyCanine
GM-Tg-bovg-SE1298-Ab-1/ GM-Tg-bovg-SE1298-Ab-2Anti-Bovine SNED1 monoclonal antibodyBovine
GM-Tg-equg-SE1298-Ab-1/ GM-Tg-equg-SE1298-Ab-2Anti-Equine SNED1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1298-Ab-1/ GM-Tg-hg-SE1298-Ab-2; GM-Tg-rg-SE1298-Ab-1/ GM-Tg-rg-SE1298-Ab-2;
GM-Tg-mg-SE1298-Ab-1/ GM-Tg-mg-SE1298-Ab-2; GM-Tg-cynog-SE1298-Ab-1/ GM-Tg-cynog-SE1298-Ab-2;
GM-Tg-felg-SE1298-Ab-1/ GM-Tg-felg-SE1298-Ab-2; GM-Tg-cang-SE1298-Ab-1/ GM-Tg-cang-SE1298-Ab-2;
GM-Tg-bovg-SE1298-Ab-1/ GM-Tg-bovg-SE1298-Ab-2; GM-Tg-equg-SE1298-Ab-1/ GM-Tg-equg-SE1298-Ab-2
Products NameAnti-SNED1 monoclonal antibody
Formatmab
Target NameSNED1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SNED1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1298-Ag-1Recombinant multi-species SNED1/ IRE-BP1/ SST3 protein


    Target information

    Target IDGM-SE1298
    Target NameSNED1
    Gene ID25992,208777,316638,717458,609463,101095844,514207,100067569
    Gene Symbol and Synonyms6720455I24Rik,D430044C15Rik,IRE-BP1,SNED1,Snep,SST3
    Uniprot AccessionQ8TER0,Q5ZQU0
    Uniprot Entry NameSNED1_HUMAN,SNED1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162804
    Target ClassificationN/A

    The target: SNED1, gene name: SNED1, also named as IRE-BP1, SST3, Snep. Predicted to enable Notch binding activity. Predicted to be involved in cell-matrix adhesion. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.