Anti-SPESP/ SPESP1/ ESP functional antibody

Anti-SPESP/ SPESP1/ ESP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SPESP1/SPESP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1308-Ab-1/ GM-Tg-hg-SE1308-Ab-2Anti-Human SPESP1 monoclonal antibodyHuman
GM-Tg-rg-SE1308-Ab-1/ GM-Tg-rg-SE1308-Ab-2Anti-Rat SPESP1 monoclonal antibodyRat
GM-Tg-mg-SE1308-Ab-1/ GM-Tg-mg-SE1308-Ab-2Anti-Mouse SPESP1 monoclonal antibodyMouse
GM-Tg-cynog-SE1308-Ab-1/ GM-Tg-cynog-SE1308-Ab-2Anti-Cynomolgus/ Rhesus macaque SPESP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1308-Ab-1/ GM-Tg-felg-SE1308-Ab-2Anti-Feline SPESP1 monoclonal antibodyFeline
GM-Tg-cang-SE1308-Ab-1/ GM-Tg-cang-SE1308-Ab-2Anti-Canine SPESP1 monoclonal antibodyCanine
GM-Tg-bovg-SE1308-Ab-1/ GM-Tg-bovg-SE1308-Ab-2Anti-Bovine SPESP1 monoclonal antibodyBovine
GM-Tg-equg-SE1308-Ab-1/ GM-Tg-equg-SE1308-Ab-2Anti-Equine SPESP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1308-Ab-1/ GM-Tg-hg-SE1308-Ab-2; GM-Tg-rg-SE1308-Ab-1/ GM-Tg-rg-SE1308-Ab-2;
GM-Tg-mg-SE1308-Ab-1/ GM-Tg-mg-SE1308-Ab-2; GM-Tg-cynog-SE1308-Ab-1/ GM-Tg-cynog-SE1308-Ab-2;
GM-Tg-felg-SE1308-Ab-1/ GM-Tg-felg-SE1308-Ab-2; GM-Tg-cang-SE1308-Ab-1/ GM-Tg-cang-SE1308-Ab-2;
GM-Tg-bovg-SE1308-Ab-1/ GM-Tg-bovg-SE1308-Ab-2; GM-Tg-equg-SE1308-Ab-1/ GM-Tg-equg-SE1308-Ab-2
Products NameAnti-SPESP1 monoclonal antibody
Formatmab
Target NameSPESP1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SPESP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1308-Ag-1Recombinant multi-species SPESP/ SPESP1/ ESP protein


    Target information

    Target IDGM-SE1308
    Target NameSPESP1
    Gene ID246777,66712,501010,694614,100684111,101099212,513571,100064996
    Gene Symbol and Synonyms4921508E09Rik,ESP,RGD1563468,SP-ESP,SPESP1
    Uniprot AccessionQ6UW49,A0JPP4,Q32KL7
    Uniprot Entry NameSPESP_HUMAN,SPESP_RAT,SPESP_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000258484
    Target ClassificationN/A

    The target: SPESP1, gene name: SPESP1, also named as ESP, SP-ESP. The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. [provided by RefSeq, Apr 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.