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Anti-SPXN/ SPX/ C12orf39 functional antibody
Anti-SPXN/ SPX/ C12orf39 functional antibody for cell culture, ELISA & in-vivo assay
Go to SPX/SPX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1320-Ab-1/ GM-Tg-hg-SE1320-Ab-2 | Anti-Human SPX monoclonal antibody | Human |
| GM-Tg-rg-SE1320-Ab-1/ GM-Tg-rg-SE1320-Ab-2 | Anti-Rat SPX monoclonal antibody | Rat |
| GM-Tg-mg-SE1320-Ab-1/ GM-Tg-mg-SE1320-Ab-2 | Anti-Mouse SPX monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1320-Ab-1/ GM-Tg-cynog-SE1320-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SPX monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1320-Ab-1/ GM-Tg-felg-SE1320-Ab-2 | Anti-Feline SPX monoclonal antibody | Feline |
| GM-Tg-cang-SE1320-Ab-1/ GM-Tg-cang-SE1320-Ab-2 | Anti-Canine SPX monoclonal antibody | Canine |
| GM-Tg-bovg-SE1320-Ab-1/ GM-Tg-bovg-SE1320-Ab-2 | Anti-Bovine SPX monoclonal antibody | Bovine |
| GM-Tg-equg-SE1320-Ab-1/ GM-Tg-equg-SE1320-Ab-2 | Anti-Equine SPX monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1320-Ab-1/ GM-Tg-hg-SE1320-Ab-2; GM-Tg-rg-SE1320-Ab-1/ GM-Tg-rg-SE1320-Ab-2; GM-Tg-mg-SE1320-Ab-1/ GM-Tg-mg-SE1320-Ab-2; GM-Tg-cynog-SE1320-Ab-1/ GM-Tg-cynog-SE1320-Ab-2; GM-Tg-felg-SE1320-Ab-1/ GM-Tg-felg-SE1320-Ab-2; GM-Tg-cang-SE1320-Ab-1/ GM-Tg-cang-SE1320-Ab-2; GM-Tg-bovg-SE1320-Ab-1/ GM-Tg-bovg-SE1320-Ab-2; GM-Tg-equg-SE1320-Ab-1/ GM-Tg-equg-SE1320-Ab-2 |
| Products Name | Anti-SPX monoclonal antibody |
| Format | mab |
| Target Name | SPX |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SPX benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1320-Ag-1 | Recombinant multi-species SPXN/ SPX/ C12orf39 protein |
Target information
| Target ID | GM-SE1320 |
| Target Name | SPX |
| Gene ID | 80763,319552,691138,706042,102151474,101096156,509493,100147193 |
| Gene Symbol and Synonyms | B230216G23Rik,C12orf39,C27H12orf39,C5H12orf39,C6H12orf39,CB4H12orf39,Npq,SPX,SPX1 |
| Uniprot Accession | Q9BT56,M0R8L2,Q0VC44 |
| Uniprot Entry Name | SPXN_HUMAN,SPXN_RAT,SPXN_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000134548 |
| Target Classification | N/A |
The target: SPX, gene name: SPX, also named as C12orf39. The protein encoded by this gene is a hormone involved in modulation of cardiovascular and renal function. It has also been shown in rats to cause weight loss. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
