Anti-SRPX2/ BPP/ CBPS functional antibody

Anti-SRPX2/ BPP/ CBPS functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SRPX2/SRPX2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1322-Ab-1/ GM-Tg-hg-SE1322-Ab-2Anti-Human SRPX2 monoclonal antibodyHuman
GM-Tg-rg-SE1322-Ab-1/ GM-Tg-rg-SE1322-Ab-2Anti-Rat SRPX2 monoclonal antibodyRat
GM-Tg-mg-SE1322-Ab-1/ GM-Tg-mg-SE1322-Ab-2Anti-Mouse SRPX2 monoclonal antibodyMouse
GM-Tg-cynog-SE1322-Ab-1/ GM-Tg-cynog-SE1322-Ab-2Anti-Cynomolgus/ Rhesus macaque SRPX2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1322-Ab-1/ GM-Tg-felg-SE1322-Ab-2Anti-Feline SRPX2 monoclonal antibodyFeline
GM-Tg-cang-SE1322-Ab-1/ GM-Tg-cang-SE1322-Ab-2Anti-Canine SRPX2 monoclonal antibodyCanine
GM-Tg-bovg-SE1322-Ab-1/ GM-Tg-bovg-SE1322-Ab-2Anti-Bovine SRPX2 monoclonal antibodyBovine
GM-Tg-equg-SE1322-Ab-1/ GM-Tg-equg-SE1322-Ab-2Anti-Equine SRPX2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1322-Ab-1/ GM-Tg-hg-SE1322-Ab-2; GM-Tg-rg-SE1322-Ab-1/ GM-Tg-rg-SE1322-Ab-2;
GM-Tg-mg-SE1322-Ab-1/ GM-Tg-mg-SE1322-Ab-2; GM-Tg-cynog-SE1322-Ab-1/ GM-Tg-cynog-SE1322-Ab-2;
GM-Tg-felg-SE1322-Ab-1/ GM-Tg-felg-SE1322-Ab-2; GM-Tg-cang-SE1322-Ab-1/ GM-Tg-cang-SE1322-Ab-2;
GM-Tg-bovg-SE1322-Ab-1/ GM-Tg-bovg-SE1322-Ab-2; GM-Tg-equg-SE1322-Ab-1/ GM-Tg-equg-SE1322-Ab-2
Products NameAnti-SRPX2 monoclonal antibody
Formatmab
Target NameSRPX2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SRPX2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1322-Ag-1Recombinant multi-species SRPX2/ BPP/ CBPS protein


    Target information

    Target IDGM-SE1322
    Target NameSRPX2
    Gene ID27286,68792,317181,700756,119868468,101085607,514742,100057264
    Gene Symbol and Synonyms1110039C07Rik,BPP,CBPS,PMGX,RESDX,RGD1562444,SRP,SRPUL,SRPX2
    Uniprot AccessionO60687,B5DF94,Q5EA25
    Uniprot Entry NameSRPX2_HUMAN,SRPX2_RAT,SRPX2_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000102359
    Target ClassificationN/A

    The target: SRPX2, gene name: SRPX2, also named as BPP, CBPS, PMGX, RESDX, SRPUL. This gene encodes a secreted protein that contains three sushi repeat motifs. The encoded protein may play a role in the development of speech and language centers in the brain. This protein may also be involved in angiogenesis. Mutations in this gene are the cause of bilateral perisylvian polymicrogyria, rolandic epilepsy, speech dyspraxia and cognitive disability. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.