Anti-SRCRL/ SSC5D/ S5D-SRCRB functional antibody

Anti-SRCRL/ SSC5D/ S5D-SRCRB functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SSC5D/SSC5D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1324-Ab-1/ GM-Tg-hg-SE1324-Ab-2Anti-Human SSC5D monoclonal antibodyHuman
GM-Tg-rg-SE1324-Ab-1/ GM-Tg-rg-SE1324-Ab-2Anti-Rat SSC5D monoclonal antibodyRat
GM-Tg-mg-SE1324-Ab-1/ GM-Tg-mg-SE1324-Ab-2Anti-Mouse SSC5D monoclonal antibodyMouse
GM-Tg-cynog-SE1324-Ab-1/ GM-Tg-cynog-SE1324-Ab-2Anti-Cynomolgus/ Rhesus macaque SSC5D monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1324-Ab-1/ GM-Tg-felg-SE1324-Ab-2Anti-Feline SSC5D monoclonal antibodyFeline
GM-Tg-cang-SE1324-Ab-1/ GM-Tg-cang-SE1324-Ab-2Anti-Canine SSC5D monoclonal antibodyCanine
GM-Tg-bovg-SE1324-Ab-1/ GM-Tg-bovg-SE1324-Ab-2Anti-Bovine SSC5D monoclonal antibodyBovine
GM-Tg-equg-SE1324-Ab-1/ GM-Tg-equg-SE1324-Ab-2Anti-Equine SSC5D monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1324-Ab-1/ GM-Tg-hg-SE1324-Ab-2; GM-Tg-rg-SE1324-Ab-1/ GM-Tg-rg-SE1324-Ab-2;
GM-Tg-mg-SE1324-Ab-1/ GM-Tg-mg-SE1324-Ab-2; GM-Tg-cynog-SE1324-Ab-1/ GM-Tg-cynog-SE1324-Ab-2;
GM-Tg-felg-SE1324-Ab-1/ GM-Tg-felg-SE1324-Ab-2; GM-Tg-cang-SE1324-Ab-1/ GM-Tg-cang-SE1324-Ab-2;
GM-Tg-bovg-SE1324-Ab-1/ GM-Tg-bovg-SE1324-Ab-2; GM-Tg-equg-SE1324-Ab-1/ GM-Tg-equg-SE1324-Ab-2
Products NameAnti-SSC5D monoclonal antibody
Formatmab
Target NameSSC5D
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SSC5D benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1324-Ag-1Recombinant multi-species SRCRL/ SSC5D/ S5D-SRCRB protein


    Target information

    Target IDGM-SE1324
    Target NameSSC5D
    Gene ID284297,269855,308341,701740,611280,101089814,530828,100072730
    Gene Symbol and SynonymsA430110N23Rik,RGD1565772,S5D-SRCRB,SSC5D
    Uniprot AccessionA1L4H1
    Uniprot Entry NameSRCRL_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000179954
    Target ClassificationN/A

    The target: SSC5D, gene name: SSC5D, also named as S5D-SRCRB. Predicted to enable fibronectin binding activity; laminin binding activity; and scavenger receptor activity. Predicted to be involved in defense response; detection of bacterial lipoprotein; and negative regulation of interleukin-8 production. Predicted to act upstream of or within regulation of interleukin-8 production. Predicted to be located in collagen-containing extracellular matrix. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.