Anti-TINAL/ TINAGL1/ ARG1 functional antibody

Anti-TINAL/ TINAGL1/ ARG1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to TINAGL1/TINAGL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1342-Ab-1/ GM-Tg-hg-SE1342-Ab-2Anti-Human TINAGL1 monoclonal antibodyHuman
GM-Tg-rg-SE1342-Ab-1/ GM-Tg-rg-SE1342-Ab-2Anti-Rat TINAGL1 monoclonal antibodyRat
GM-Tg-mg-SE1342-Ab-1/ GM-Tg-mg-SE1342-Ab-2Anti-Mouse TINAGL1 monoclonal antibodyMouse
GM-Tg-cynog-SE1342-Ab-1/ GM-Tg-cynog-SE1342-Ab-2Anti-Cynomolgus/ Rhesus macaque TINAGL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1342-Ab-1/ GM-Tg-felg-SE1342-Ab-2Anti-Feline TINAGL1 monoclonal antibodyFeline
GM-Tg-cang-SE1342-Ab-1/ GM-Tg-cang-SE1342-Ab-2Anti-Canine TINAGL1 monoclonal antibodyCanine
GM-Tg-bovg-SE1342-Ab-1/ GM-Tg-bovg-SE1342-Ab-2Anti-Bovine TINAGL1 monoclonal antibodyBovine
GM-Tg-equg-SE1342-Ab-1/ GM-Tg-equg-SE1342-Ab-2Anti-Equine TINAGL1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1342-Ab-1/ GM-Tg-hg-SE1342-Ab-2; GM-Tg-rg-SE1342-Ab-1/ GM-Tg-rg-SE1342-Ab-2;
GM-Tg-mg-SE1342-Ab-1/ GM-Tg-mg-SE1342-Ab-2; GM-Tg-cynog-SE1342-Ab-1/ GM-Tg-cynog-SE1342-Ab-2;
GM-Tg-felg-SE1342-Ab-1/ GM-Tg-felg-SE1342-Ab-2; GM-Tg-cang-SE1342-Ab-1/ GM-Tg-cang-SE1342-Ab-2;
GM-Tg-bovg-SE1342-Ab-1/ GM-Tg-bovg-SE1342-Ab-2; GM-Tg-equg-SE1342-Ab-1/ GM-Tg-equg-SE1342-Ab-2
Products NameAnti-TINAGL1 monoclonal antibody
Formatmab
Target NameTINAGL1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TINAGL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1342-Ag-1Recombinant multi-species TINAL/ TINAGL1/ ARG1 protein
    ORF Viral VectorvGMLP003135human TINAGL1 Lentivirus particle
    ORF Viral VectorpGMLV000543human TINAGL1 Lentivirus plasmid
    ORF Viral VectorvGMLV000066human TINAGL1 Lentivirus particle
    ORF Viral VectorvGMLV000543human TINAGL1 Lentivirus particle
    ORF Viral VectorpGMLP003135human TINAGL1 Lentivirus plasmid
    ORF Viral VectorpGMLV000066human TINAGL1 Lentivirus plasmid
    ORF Viral VectorpGMLPm005288mouse Tinagl1 Lentivirus plasmid
    ORF Viral VectorvGMLPm005288mouse Tinagl1 Lentivirus particle


    Target information

    Target IDGM-SE1342
    Target NameTINAGL1
    Gene ID64129,94242,94174,705660,478155,101101397,509642,100056208
    Gene Symbol and Synonyms1110021J17Rik,ARG1,AZ-1,AZ1,gis5,LCN7,LIECG3,TARP,Tinagl,TINAGL1,TINAGRP
    Uniprot AccessionQ9GZM7,Q9EQT5
    Uniprot Entry NameTINAL_HUMAN,TINAL_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000142910
    Target ClassificationN/A

    The target: TINAGL1, gene name: TINAGL1, also named as ARG1, LCN7, LIECG3, TINAGRP. The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.