Anti-VWA1/ WARP functional antibody

Anti-VWA1/ WARP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to VWA1/VWA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1364-Ab-1/ GM-Tg-hg-SE1364-Ab-2Anti-Human VWA1 monoclonal antibodyHuman
GM-Tg-rg-SE1364-Ab-1/ GM-Tg-rg-SE1364-Ab-2Anti-Rat VWA1 monoclonal antibodyRat
GM-Tg-mg-SE1364-Ab-1/ GM-Tg-mg-SE1364-Ab-2Anti-Mouse VWA1 monoclonal antibodyMouse
GM-Tg-cynog-SE1364-Ab-1/ GM-Tg-cynog-SE1364-Ab-2Anti-Cynomolgus/ Rhesus macaque VWA1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1364-Ab-1/ GM-Tg-felg-SE1364-Ab-2Anti-Feline VWA1 monoclonal antibodyFeline
GM-Tg-cang-SE1364-Ab-1/ GM-Tg-cang-SE1364-Ab-2Anti-Canine VWA1 monoclonal antibodyCanine
GM-Tg-bovg-SE1364-Ab-1/ GM-Tg-bovg-SE1364-Ab-2Anti-Bovine VWA1 monoclonal antibodyBovine
GM-Tg-equg-SE1364-Ab-1/ GM-Tg-equg-SE1364-Ab-2Anti-Equine VWA1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1364-Ab-1/ GM-Tg-hg-SE1364-Ab-2; GM-Tg-rg-SE1364-Ab-1/ GM-Tg-rg-SE1364-Ab-2;
GM-Tg-mg-SE1364-Ab-1/ GM-Tg-mg-SE1364-Ab-2; GM-Tg-cynog-SE1364-Ab-1/ GM-Tg-cynog-SE1364-Ab-2;
GM-Tg-felg-SE1364-Ab-1/ GM-Tg-felg-SE1364-Ab-2; GM-Tg-cang-SE1364-Ab-1/ GM-Tg-cang-SE1364-Ab-2;
GM-Tg-bovg-SE1364-Ab-1/ GM-Tg-bovg-SE1364-Ab-2; GM-Tg-equg-SE1364-Ab-1/ GM-Tg-equg-SE1364-Ab-2
Products NameAnti-VWA1 monoclonal antibody
Formatmab
Target NameVWA1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VWA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1364-Ag-1Recombinant multi-species VWA1/ WARP protein


    Target information

    Target IDGM-SE1364
    Target NameVWA1
    Gene ID64856,246228,298683,701765,607112,101086047,505917,111772476
    Gene Symbol and Synonyms4932416A11Rik,HMNMYO,RGD1311476,VWA1,WARP
    Uniprot AccessionQ6PCB0,Q642A6,A6QLN9
    Uniprot Entry NameVWA1_HUMAN,VWA1_RAT,VWA1_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000179403
    Target ClassificationN/A

    The target: VWA1, gene name: VWA1, also named as WARP. VWA1 belongs to the von Willebrand factor (VWF; MIM 613160) A (VWFA) domain superfamily of extracellular matrix proteins and appears to play a role in cartilage structure and function (Fitzgerald et al., 2002 [PubMed 12062410]).[supplied by OMIM, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.